Identification
Name: Glutathione-regulated potassium-efflux system protein kefB
Synonyms:
  • K(+)/H(+) antiporter
  • NEM-activable K(+)/H(+) antiporter
Gene Name: kefB
Enzyme Class: Not Available
Biological Properties
General Function: Involved in solute:hydrogen antiporter activity
Specific Function: Transport system that facilitates potassium-efflux, possibly by potassium-proton antiport
Cellular Location: Cell inner membrane; Multi-pass membrane protein
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    K+[periplasm] → K+[cytosol]
    ReactionCard
    Complex Reactions: Not Available
    Transports:
    Metabolites:
    PAMDB IDNameView
    PAMDB001633Hydrogen ionMetaboCard
    PAMDB000632PotassiumMetaboCard
    GO Classification:
    Component
    cell part
    integral to membrane
    intrinsic to membrane
    membrane
    membrane part
    plasma membrane
    Function
    binding
    catalytic activity
    cation transmembrane transporter activity
    glutathione-regulated potassium exporter activity
    inorganic cation transmembrane transporter activity
    ion transmembrane transporter activity
    monovalent inorganic cation transmembrane transporter activity
    potassium ion transmembrane transporter activity
    solute:cation antiporter activity
    solute:hydrogen antiporter activity
    substrate-specific transmembrane transporter activity
    transmembrane transporter activity
    transporter activity
    Process
    cation transport
    establishment of localization
    ion transport
    metabolic process
    monovalent inorganic cation transport
    potassium ion transport
    transmembrane transport
    transport
    Gene Properties
    Locus tag: PA1207
    Strand: +
    Entrez Gene ID: 881881
    Accession: NP_249898.1
    GI: 15596404
    Sequence start: 1306059
    Sequence End: 1307900
    Sequence Length: 1841
    Gene Sequence:
    >PA1207
    GTGGAACACGGAAGCAGTTTTCTCCAGTCCGGCGTGGTCTTCCTGATCGCGGCGGTGTTCATGGTGCCGCTGGCCAAGCGTCTGCAACTGGGCGCGGTGCTCGGCTACCTGCTGGCCGGCGTGCTGATCGGTCCCAGCGTGCTGGGCCTGGTGGACAACCCGGAAAGCGTCGCGCAGATCTCCGAGATGGGCGTGGTATTGCTGCTGTTCATCATCGGCCTGGAGCTGTCGCCGCGGCGCCTGTGGGTGATGCGCAAGTCGGTGTTCGGCGTCGGCCTGCTGCAGGTGCTGCTGACCGGCCTGGTGATCGGCACCGTGGCCCTGGTCGGCTTCGACCAGCCGGTGAACAGCGCGGTGGTGCTCGGCCTGGGCCTGGCGCTGTCGTCCACCGCCTTCGGCCTGCAGATCCTCGCCGAGCGCAAGGAACTGACCCAGCCCCATGGCCGCCTGGCCTTCGCCATCCTGCTGTTCCAGGACATCGCGGCGATCCCGCTGATCGCCATGATCCCGCTGCTCAGCGGTGCGCACAGCGACGCCGGCGGCAGCGAACTGACCCAGACCCTCAAGGTGGTCGGCAGCATCGCCGCGGTGGTGGTCGGTGGCCGCTACCTGCTGCGCCCGGTGTTCCGTATCGTCGCCCAGACCAAGCTGCAGGACATGTCCACCGCCACCGCGCTGCTGGTGGTGATGGGCACCGCGCTGCTGATGGAGCTGGCCGGCGTGTCCATGGCCCTCGGTGCCTTCCTCGCCGGCCTGCTGCTGGCCGACTCGGAGTACCGCCACGAACTGGAGGCGCAGATCGAGCCGTTCAAGGGCCTGTTGCTCGGCCTGTTCTTCATCAGCGTGGGGATGAGCGCGGACATCAGCCTGCTGCTCAAGTCGCCGTGGATGGTGCTCGGCCTGACCGTGCTGCTGATCGCCCTGAAGGCGCCGGTGCTGTACTTCGTCGGACGCATTTCCGGCGGCCTCGACAAGGCCTCGGCGCTGCGCCTGGGCGTGGTCCTGGCGGCCGGCGGCGAGTTCGCCTTCGTCGTGTTCAAGATGGCCCGCGACCAGGGCCTGTTCCAGAACGACCTGCACAACCTGCTGGTGCTTTCCATCACCCTGTCGATGGCCCTGACCCCGTTGCTGGTACTCGGCCTCGCGCGCCTGCTGGCGAAGGAGCCGGAGGCGACGAAGCCGCCGCCGGAAATGGAACGCATCGACAACGACGACACCCCGCGCGTGGTGATCGCCGGGGTCGGCCGCATGGGCCAGATCGTCGCTCGCGTGCTGCGCGCCCAGCGCGTGCCGTTCATCGCCCTGGACACCTCGGTGGAGACCATCGAGCTGACCCGTACCCTCGGCGCGATCCCGATCTTCTACGGCGACCCGATGCGCCCGGAGATCCTTCGCGCGGCCCAGGTAGAGAAGGCCGAGTTCTTCGTCATCGCCACCGATGACCCGGAGACCAACATCGAGACGGCCAAGCGCGTGCGCAAGCTGTATCCGCACCTGAAGATCATCGCTCGCGCGCGTAACCGCCAGCACGTCCACCTGTTGCTCGACGCCGGGGTCGAGCCGGTGCGCGAGACCTTCTTCTCCAGCCTGGAGATGAGCCGCATGGTGCTCTGCGGCCTGGGTCTGAGCGAGGAACAGGCGGACGCGCGGATCCGTCGTTTCCGCCGGCACGACGAAGAGGTCCTGGCCTCCCAGCACCTGTTCTACAACGACCGCGACGCGCTGATCAAAAGCGCTCGCGAGGCGCGGGTCGAGCTGGAGACGCTGTTCCAGACCGACCAGTTGGAAGACCGTGGCGCGGTAGCGGCGGAGACCCCGGAGAAACCTTCCCGCGCCTCCTAG
    Protein Properties
    Protein Residues: 613
    Protein Molecular Weight: 66.3 kDa
    Protein Theoretical pI: 6.88
    Hydropathicity (GRAVY score): 0.496
    Charge at pH 7 (predicted): -0.6
    Protein Sequence:
    >PA1207
    MEHGSSFLQSGVVFLIAAVFMVPLAKRLQLGAVLGYLLAGVLIGPSVLGLVDNPESVAQISEMGVVLLLFIIGLELSPRRLWVMRKSVFGVGLLQVLLTGLVIGTVALVGFDQPVNSAVVLGLGLALSSTAFGLQILAERKELTQPHGRLAFAILLFQDIAAIPLIAMIPLLSGAHSDAGGSELTQTLKVVGSIAAVVVGGRYLLRPVFRIVAQTKLQDMSTATALLVVMGTALLMELAGVSMALGAFLAGLLLADSEYRHELEAQIEPFKGLLLGLFFISVGMSADISLLLKSPWMVLGLTVLLIALKAPVLYFVGRISGGLDKASALRLGVVLAAGGEFAFVVFKMARDQGLFQNDLHNLLVLSITLSMALTPLLVLGLARLLAKEPEATKPPPEMERIDNDDTPRVVIAGVGRMGQIVARVLRAQRVPFIALDTSVETIELTRTLGAIPIFYGDPMRPEILRAAQVEKAEFFVIATDDPETNIETAKRVRKLYPHLKIIARARNRQHVHLLLDAGVEPVRETFFSSLEMSRMVLCGLGLSEEQADARIRRFRRHDEEVLASQHLFYNDRDALIKSAREARVELETLFQTDQLEDRGAVAAETPEKPSRAS
    References
    External Links:
    Resource Link
    Genome ID: PA1207
    Entrez Gene ID: 881881
    NCBI Protein ID: 15596404
    General Reference: PaperBLAST - Find papers about PA1207 and its homologs