tRNA (guanine-N(7)-)-methyltransferase (PA0382)

Identification
Name: tRNA (guanine-N(7)-)-methyltransferase
Synonyms:
  • tRNA(m7G46)-methyltransferase
Gene Name: trmB
Enzyme Class:
Biological Properties
General Function: Involved in tRNA (guanine-N7-)-methyltransferase activity
Specific Function: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
Cellular Location: Not Available
KEGG Pathways: Not Available
KEGG Reactions:
Thumb ↔ Thumb
S-Adenosylmethionine ↔ S-Adenosylhomocysteine
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb ↔ Thumb
S-Adenosylmethionine ↔ S-Adenosylhomocysteine
ReactionCard
Guanine46-in-tRNA+PAMDB000289 → tRNA-Containing-N7-Methylguanine-46+PAMDB000205
Guanine46-in-tRNA + S-Adenosylmethionine → tRNA-Containing-N7-Methylguanine-46 + S-Adenosylhomocysteine
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000205S-AdenosylhomocysteineMetaboCard
GO Classification:
Function
catalytic activity
methyltransferase activity
RNA methyltransferase activity
transferase activity
transferase activity, transferring one-carbon groups
tRNA (guanine) methyltransferase activity
tRNA (guanine-N7-)-methyltransferase activity
tRNA methyltransferase activity
Process
cellular macromolecule metabolic process
macromolecule metabolic process
metabolic process
ncRNA metabolic process
RNA metabolic process
tRNA metabolic process
tRNA modification
tRNA processing
Gene Properties
Locus tag: PA0382
Strand: +
Entrez Gene ID: 879787
Accession: NP_249073.1
GI: 15595579
Sequence start: 424670
Sequence End: 425341
Sequence Length: 671
Gene Sequence: 
>PA0382
ATGCGCACCGTGAAGAGCTTCGTGATGCGCGCCGGGCGCATGACCGAAGGCCAGCAGCGTGGCCTCGACCTGGGCTGGCCGAAGTTCGGCCTGGAACTGAGCGATGAGGTCCAGGACTTCGACGCGATCTTCGGTCGCCAGGCGCCGCGGACTTTCGAGATCGGTTTCGGCATGGGCCATTCCACCCTGGAAATGGCCGCCGCTGCGCCTGACATCGACTTCATCGGCGTCGAGGTGCACAAGCCGGGCGTCGGCGCGCTGCTCAACGGCCTGCTGACCCAGGGCCTGGGCAACGTGCGGGTGTATAGCTGCGACGCGCTGGAAGTGCTGCGCCACTGCGTGGCCGACGCCAGCCTCGATCGGCTGCTGCTGTTCTTCCCCGATCCCTGGCACAAGAAGCGCCACCACAAGCGGCGGATCGTCCAGCCGGAATTCGCCGAACTGGTGCGGCGCAAGCTGAAGGTCGGCGGCGTGCTGCACATGGCCACCGACTGGGAGCCCTATGCCGAGCACATGCTGGACGTCATGAGCGCGGCGCCGGGCTACCGCAACCAGGCCGAAGACGGCCGCTTCGTGCCGCGCCCGCAAGAGCGTCCGGTGACCAAGTTCGAGCGGCGCGGGGAGCGCCTGGGACATGGCGTCTGGGACCTCAAGTTCGAGCGCGTCGACTGA
Protein Properties
Protein Residues: 223
Protein Molecular Weight: 25.3 kDa
Protein Theoretical pI: 8.28
Hydropathicity (GRAVY score): -0.385
Charge at pH 7 (predicted): 3.1
Protein Sequence: 
>PA0382
MRTVKSFVMRAGRMTEGQQRGLDLGWPKFGLELSDEVQDFDAIFGRQAPRTFEIGFGMGHSTLEMAAAAPDIDFIGVEVHKPGVGALLNGLLTQGLGNVRVYSCDALEVLRHCVADASLDRLLLFFPDPWHKKRHHKRRIVQPEFAELVRRKLKVGGVLHMATDWEPYAEHMLDVMSAAPGYRNQAEDGRFVPRPQERPVTKFERRGERLGHGVWDLKFERVD
References
External Links:
Resource Link
Genome ID: PA0382
Entrez Gene ID: 879787
NCBI Protein ID: 15595579
General Reference: PaperBLAST - Find papers about PA0382 and its homologs