Shikimate dehydrogenase (PA0025)

Identification
Name: Shikimate dehydrogenase
Synonyms: Not Available
Gene Name: aroE
Enzyme Class:
Biological Properties
General Function: Involved in nucleotide binding
Specific Function: Shikimate + NADP(+) = 3-dehydroshikimate + NADPH
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb+Thumb ↔ Thumb+Thumb
3-Dehydro-shikimate + Hydrogen ion + NADPH ↔ NADP + Shikimic acid
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb+Thumb
Shikimic acid + NADP ↔ 3-Dehydro-shikimate + NADPH + Hydrogen ion
ReactionCard
SMPDB Reactions:
3-dehydroshikimate+NADPH+Thumb+Thumb+Thumb → Thumb+Thumb
3-dehydroshikimate + NADPH + Hydrogen ion + 3-Dehydro-shikimate + NADPH → NADP + Shikimic acid
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb+Thumb ↔ Thumb+Thumb
3-Dehydro-shikimate + Hydrogen ion + NADPH ↔ NADP + Shikimic acid
ReactionCard
Thumb+Thumb ← Thumb+Thumb+Thumb
NADP + Shikimic acid ← Hydrogen ion + NADPH + 3-Dehydro-shikimate
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0005813-Dehydro-shikimateMetaboCard
PAMDB000452Gallic acidMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000089NADPMetaboCard
PAMDB000615NADPHMetaboCard
PAMDB000477Shikimic acidMetaboCard
GO Classification:
Component
cell part
cytoplasm
intracellular part
Function
binding
catalytic activity
NADP or NADPH binding
nucleotide binding
oxidoreductase activity
oxidoreductase activity, acting on CH-OH group of donors
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
shikimate 5-dehydrogenase activity
Process
metabolic process
oxidation reduction
Gene Properties
Locus tag: PA0025
Strand: +
Entrez Gene ID: 880894
Accession: NP_248715.1
GI: 15595223
Sequence start: 26711
Sequence End: 27535
Sequence Length: 824
Gene Sequence: 
>PA0025
ATGGACCGCTATTGCGTATTCGGCAACCCCATCGGCCACAGCAAGTCGCCGCTGATCCACCGCCTGTTCGCCGAGCAGACCGGCGAGGCGCTGGTCTATGACGCGCAACTGGCGCCGCTGGACGATTTCCCCGGGTTCGCCCGGCGCTTCTTCGAGCAGGGCAAGGGCGCCAATGTCACCGTGCCGTTCAAGGAAGAGGCCTATCGTCTGGTGGACGAGTTGAGCGAGCGGGCCACCCGGGCCGGGGCGGTGAACACCCTGATCCGCCTCGCCGACGGTCGCCTGCGCGGCGACAACACCGACGGCGCCGGCCTGCTGCGGGACCTGACGGCGAACGCCGGGGTCGAGCTGCGCGGCAAGCGGGTTCTCCTGCTCGGCGCCGGCGGTGCGGTGCGTGGGGTGCTCGAACCCTTCCTCGGCGAGTGCCCGGCGGAGTTGCTGATCGCCAACCGCACGGCGCGGAAGGCCGTGGACCTGGCCGAGCGGTTCGCCGACCTCGGCGCGGTGCACGGCTGCGGTTTCGCCGAGGTCGAAGGGCCTTTCGACCTGATCGTCAACGGCACCTCGGCCAGTCTTGCCGGCGACGTGCCGCCGCTGGCGCAGAGCGTGATCGAGCCCGGCCGTACCGTCTGCTACGACATGATGTATGCCAAGGAACCGACTGCCTTCAACCGCTGGGCCGCCGAACGCGGTGCGGCGCGTACCCTGGATGGCCTGGGCATGCTGGTGGAGCAGGCCGCCGAGGCATTCTTCCTCTGGCGCGGCGTGCGTCCTGCCTCGGCGCCAGTGTTGGAGACGCTGCGCCGACAGTTGGCAACTGTCTGA
Protein Properties
Protein Residues: 274
Protein Molecular Weight: 29.5 kDa
Protein Theoretical pI: 5.46
Hydropathicity (GRAVY score): -0.023
Charge at pH 7 (predicted): -3.39
Protein Sequence: 
>PA0025
MDRYCVFGNPIGHSKSPLIHRLFAEQTGEALVYDAQLAPLDDFPGFARRFFEQGKGANVTVPFKEEAYRLVDELSERATRAGAVNTLIRLADGRLRGDNTDGAGLLRDLTANAGVELRGKRVLLLGAGGAVRGVLEPFLGECPAELLIANRTARKAVDLAERFADLGAVHGCGFAEVEGPFDLIVNGTSASLAGDVPPLAQSVIEPGRTVCYDMMYAKEPTAFNRWAAERGAARTLDGLGMLVEQAAEAFFLWRGVRPASAPVLETLRRQLATV
References
External Links:
Resource Link
Genome ID: PA0025
Entrez Gene ID: 880894
NCBI Protein ID: 15595223
General Reference: PaperBLAST - Find papers about PA0025 and its homologs