PG(19:0cycv8c/19:iso) (PAMDB004102)

General function:

Lipid transport and metabolism

Specific function:

2-lysophosphatidylcholine + H(2)O = glycerophosphocholine + a carboxylate

Gene Name:

pldB

Locus Tag:

PA5089

Molecular weight:

83.4 kDa

Reactions

General function:

Involved in phosphatidylglycerophosphatase activity

Specific function:

One of the three phospholipid phosphatases, specifically hydrolyzes phosphatidylglycerophosphate

Gene Name:

pgpA

Locus Tag:

PA4050

Molecular weight:

19.6 kDa

Reactions

General function:

Involved in nucleotide binding

Specific function:

Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation

Gene Name:

msbA

Locus Tag:

PA4997

Molecular weight:

66.4 kDa

General function:

Involved in phosphotransferase activity, for other substituted phosphate groups

Specific function:

Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Affects resistance to the gyrase inhibitor novobiocin

Gene Name:

cls

Locus Tag:

PA5394

Molecular weight:

54.6 kDa

Reactions

General function:

Involved in catalytic activity

Specific function:

Catalyzes, in vitro, the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Can also catalyze phosphatidyl group transfer to water to form phosphatidate. Catalyzes little, if any, cardiolipin synthesis in vivo, even when the expression level is very high

Gene Name:

ybhO

Locus Tag:

PA2155

Molecular weight:

46.5 kDa

Reactions