Search Results for compounds

Searching compounds for returned 4373 results.
Displaying compounds 3041 - 3050 of 4373 in total

colistin  (PAMDB100067)

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IUPAC: N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(6R,9S,12R,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydr
CAS: Not Available
Description: A multi-component mixture comprising mostly of colistin A (R = Me) and B (R = H), with small amounts of colistin C and other polymyxins, produced by certain strains of Bacillus polymyxa var. colistinus. An antibiotic, it is used as its sulfa

colistimethate  (PAMDB100068)

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IUPAC: [2-[17-(1-hydroxyethyl)-22-[[2-[[3-hydroxy-2-[[2-(6-methyloctanoylamino)-4-(sulfonatomethylamino)butanoyl]amino]butanoyl]amino]-4-(sulfonatomethylamino)butanoyl]amino]-5,8-bis(2-methylpropyl)-3,6,9,12,15,18,23-heptaoxo-11,14-bis[2-(sulfonatomethylamino)et
CAS: Not Available
Description: A mixture where R = H or Me. Colistin in which each of the primary amino groups is converted to the corresponding aminomethanesulfonic acid. It is prepared from colistin by the action of formaldehyde followed by sodium bisulfite. A polymyxin antibiotic, i

2-heptyl-3-hydroxy-4-quinolone  (PAMDB100069)

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IUPAC:

2-heptyl-3-hydroxy-1H-quinolin-4-one

CAS: Not Available
Description:

The Pseudomonas quinolone signal (PQS) is a quorum sensing molecule unique to Pseudomonas aeruginosa. This molecule is active when the density of bacterial cells reaches a quorum. PQS is an important signaling molecule that enhances the production of virulence factors by P. aeruginosa including the production of phenazines and elastases. PQS has also been reported to chelate ferric iron and induce vesicle formation at the membrane. PQS is produced from the hydroxylation of HHQ by mono-oxygenase PqsH.


3-hydroxy-2-methyl-4(1H)-quinolone (C9-PQS)  (PAMDB100070)

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IUPAC:

2-nonyl-3-hydroxy-4-quinolone

CAS: Not Available
Description:

C9-PQS is a PQS analog. It is predicted to have similar function as PQS (C7-PQS) which is a quorum sensing molecule unique to Pseudomonas aeruginosa. Predicted properties based on analogy to PQS.


C11-PQS  (PAMDB100071)

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IUPAC: 2-undecyl-3-hydroxy-4-quinolone
CAS: Not Available
Description:

C11-PQS is a PQS analog. It is predicted to have similar function as PQS (C7-PQS) which is a quorum sensing molecule unique to Pseudomonas aeruginosa. Predicted properties based on analogy to PQS.


2-heptyl-4-quinolone  (PAMDB100072)

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IUPAC:

2-heptyl-1,4-dihydroquinolin-4-one

CAS: 2503-80-2
Description:

2-heptyl-4-quinolone (HHQ) is an important quorum signaling molecule in P. aeruginosa. HHQ is involved in modulating swarming motility and inducing virulence gene expression in P. aeruginosa. HHQ is the precursor of PQS (Pseudomonas quinolone signal).


2-nonyl-4-hydroxyquinoline (NHQ)  (PAMDB100073)

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IUPAC:

2-nonyl-4-quinolinol

CAS: Not Available
Description:

2-nonyl-4-hydroxyquinoline (NHQ) is a C9 congener of HHQ which is an important quorum signaling molecule in P. aeruginosa. NHQ properties are predicted based on analogy to HHQ.


2-undecyl-4-hydroxyquinoline (UHQ)  (PAMDB100074)

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IUPAC:

2-undecyl-4-quinolinol

CAS: Not Available
Description:

2-undecyl-4-hydroxyquinoline (UHQ) is a C11 congener of HHQ which is an important quorum signaling molecule in P. aeruginosa. UHQ properties are predicted based on analogy to HHQ.


2-Heptyl-4-quinolinol 1-oxide  (PAMDB100075)

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IUPAC:

2-heptyl-4-hydroxyquinolin-1-ium-1-olate

CAS: Not Available
Description:

2-Heptyl-4-quinolinol 1 –oxide (HQNO) is an N-oxide ubiquinone analog that inhibits activity of cytochrome b1 complex, thus inhibiting respiration of Gram-Positive bacteria such as Staphylococcus aureus. HQNO has been shown to induce small colony variants (SCVs) and fermentative metabolism is S. aureus. HQNO is produced from the activity of the PqsL mono-oxygenase protein in Pseudomonas aeruginosa.


1-Hydroxy-2-nonyl-4(1H)-quinolinone  (PAMDB100076)

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IUPAC:

1-hydroxy-2-nonyl-1,4-dihydroquinolin-4-one

CAS: Not Available
Description:

1-Hydroxy-2-nonyl-4(1H)-quinolinone (NQNO) is a C9- congener of HQNO in P. aeruginosa. NQNO is predicted to function similarly to HQNO, an N-oxide ubiquinone analog that inhibits activity of cytochrome b1 complex.