Reaction 21927

Reaction Details
Reaction: Thumb
acetyl-CoA + a [Co(I) corrinoid Fe-S protein] + H+ ← carbon monoxide + a [methyl-Co(III) corrinoid Fe-S protein] + coenzyme A
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:ACETYLSYNCLTH-RXN
References:
  • Doukov TI, Iverson TM, Seravalli J, Ragsdale SW, Drennan CL (2002). "A Ni-Fe-Cu center in a bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase." Science 298(5593);567-72. PMID: 12386327
  • Ragsdale SW, Wood HG (1985). "Acetate biosynthesis by acetogenic bacteria. Evidence that carbon monoxide dehydrogenase is the condensing enzyme that catalyzes the final steps of the synthesis." J Biol Chem 260(7);3970-7. PMID: 2984190