Reaction 21877

Reaction Details
Reaction: Thumb
isovaleryl-CoA + an [apo BCAA dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine ← a [apo BCAA dehydrogenase E2 protein] N6-S-[3-methylbutanoyl]dihydrolipoyl-L-lysine + coenzyme A
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:ISOVALERYLCOA-DHLIPOAMIDE-RXN
References:
  • Chuang DT, Hu CC, Ku LS, Niu WL, Myers DE, Cox RP (1984). "Catalytic and structural properties of the dihydrolipoyl transacylase component of bovine branched-chain alpha-keto acid dehydrogenase." J Biol Chem 259(14);9277-84. PMID: 6746648
  • Massey LK, Sokatch JR, Conrad RS (1976). "Branched-chain amino acid catabolism in bacteria." Bacteriol Rev 40(1);42-54. PMID: 773366
  • Perham RN (2000). "Swinging arms and swinging domains in multifunctional enzymes: catalytic machines for multistep reactions." Annu Rev Biochem 69;961-1004. PMID: 10966480
  • Wynn RM, Davie JR, Zhi W, Cox RP, Chuang DT (1994). "In vitro reconstitution of the 24-meric E2 inner core of bovine mitochondrial branched-chain alpha-keto acid dehydrogenase complex: requirement for chaperonins GroEL and GroES." Biochemistry 33(30);8962-8. PMID: 7913832