Reaction 21871

Reaction Details
Reaction: Thumb
L-kynurenine + NADPH + oxygen + H+ → 3-hydroxy-L-kynurenine + NADP+ + H2O
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:KYNURENINE-3-MONOOXYGENASE-RXN
References:
  • Okamoto H, Hayaishi O (1967). "Flavin adenine dinucleotide requirement for kynurenine hydroxylase of rat liver mitochondria." Biochem Biophys Res Commun 29(3);394-9. PMID: 6076241
  • SAITO Y, HAYAISHI O, ROTHBERG S (1957). "Studies on oxygenases; enzymatic formation of 3-hydroxy-L-kynurenine from L-kynurenine." J Biol Chem 229(2);921-34. PMID: 13502353