Reaction 21787

Reaction Details
Reaction: Thumb
3-amino-1-hydroxyacetone 1-phosphate + 1-deoxy-D-xylulose 5-phosphate → pyridoxine 5'-phosphate + phosphate + H+ + 2 H2O
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:PDXJ-RXN
References:
  • Franco MG, Laber B, Huber R, Clausen T (2001). "Structural basis for the function of pyridoxine 5'-phosphate synthase." Structure 9(3);245-53. PMID: 11286891
  • Garrido-Franco M, Laber B, Huber R, Clausen T (2002). "Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis." J Mol Biol 321(4);601-12. PMID: 12206776
  • Garrido-Franco M (2003). "Pyridoxine 5'-phosphate synthase: de novo synthesis of vitamin B6 and beyond." Biochim Biophys Acta 1647(1-2);92-7. PMID: 12686115
  • Laber B, Maurer W, Scharf S, Stepusin K, Schmidt FS (1999). "Vitamin B6 biosynthesis: formation of pyridoxine 5'-phosphate from 4-(phosphohydroxy)-L-threonine and 1-deoxy-D-xylulose-5-phosphate by PdxA and PdxJ protein." FEBS Lett 1999;449(1);45-8. PMID: 10225425