Reaction Details
Reaction: Thumb
hydrogen carbonate + 3-methylcrotonyl-CoA + ATP → 3-methylglutaconyl-CoA + ADP + phosphate + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:METHYLCROTONYL-COA-CARBOXYLASE-RXN
References:
  • Aguilar JA, Zavala AN, Diaz-Perez C, Cervantes C, Diaz-Perez AL, Campos-Garcia J (2006). "The atu and liu clusters are involved in the catabolic pathways for acyclic monoterpenes and leucine in Pseudomonas aeruginosa." Appl Environ Microbiol 72(3);2070-9. PMID: 16517656
  • Hoschle B, Gnau V, Jendrossek D (2005). "Methylcrotonyl-CoA and geranyl-CoA carboxylases are involved in leucine/isovalerate utilization (Liu) and acyclic terpene utilization (Atu), and are encoded by liuB/liuD and atuC/atuF, in Pseudomonas aeruginosa." Microbiology 151(Pt 11);3649-56. PMID: 16272386
  • KNAPPE J, SCHLEGEL HG, LYNEN F (1961). "[On the biochemical function of biotin. I. The participation of beta-methyl-crotonyl-carboxylase in the formation of beta-hydroxy-beta-methyl-glutaryl-CoA from beta-hydroxy-isovaleryl-CoA]." Biochem Z 335;101-22. PMID: 14457200
  • Lynen, F, Knappe, J, Lorch, E, Juetting, G, Ringelmann, E, Lachance, JP (1961). "[On the biochemical function of biotin. II. Purification and mode of action of beta-methyl-crotonyl-carboxylase.]." Biochem Z 335;123-67. PMID: 14467590
  • Rilling, H.C., Coon, M.J. (1960). "The enzymatic isomerization of alpha-methylvinylacetyl coenzyme A and the specificity of a bacterial alpha-methylcrotonyl coenzyme A carboxylase." J Biol Chem 235;3087-92. PMID: 13741692