Reaction 21768

Reaction Details
Reaction: Thumb
a 5,10-methylene-tetrahydrofolate + NADP+ ↔ a 5,10-methenyltetrahydrofolate + NADPH
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:METHYLENETHFDEHYDROG-NADP-RXN
References:
  • HATEFI Y, OSBORN MJ, KAY LD, HUENNEKENS FM (1957). "Hydroxymethyl tetrahydrofolic dehydrogenase." J Biol Chem 227(2);637-47. PMID: 13462986
  • OSBORN MJ, HUENNEKENS FM (1957). "Participation of anhydroleucovorin in the hydroxymethyl tetrahydrofolic dehydrogenase system." Biochim Biophys Acta 26(3);646-7. PMID: 13499428
  • RAMASASTRI BV, BLAKLEY RL (1962). "5,10-Methylenetetrahydrofolic dehydrogenase from bakers' yeast. I. Partial purification and some properties." J Biol Chem 237;1982-8. PMID: 14490085
  • Yeh YC, Greenberg DM (1965). "Purification and properties of N5, N10-Methylenetetra-hydrofolate dehydrogenase of calf thymus." Biochim Biophys Acta 105(2);279-91. PMID: 4379024