Reaction 21736

Reaction Details
Reaction: Thumb
3-phospho-D-glycerate + NAD+ → 3-phospho-hydroxypyruvate + NADH + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:PGLYCDEHYDROG-RXN
References:
  • Pizer LI (1963). "The pathway and control of serine biosynthesis in Escherichia coli." J Biol Chem 1963;238:3934-3944. PMID: 14086727
  • Schuller DJ, Grant GA, Banaszak LJ (1995). "The allosteric ligand site in the Vmax-type cooperative enzyme phosphoglycerate dehydrogenase." Nat Struct Biol 2(1);69-76. PMID: 7719856
  • Sugimoto E, Pizer LI (1968). "The mechanism of end product inhibition of serine biosynthesis. I. Purification and kinetics of phosphoglycerate dehydrogenase." J Biol Chem 1968;243(9);2081-9. PMID: 4384871
  • Zhao G, Winkler ME (1996). "A novel alpha-ketoglutarate reductase activity of the serA-encoded 3-phosphoglycerate dehydrogenase of Escherichia coli K-12 and its possible implications for human 2-hydroxyglutaric aciduria." J Bacteriol 1996;178(1);232-9. PMID: 8550422