Reaction 21691

Reaction Details
Reaction: Thumb
an alkylated DNA + H2O → DNAn + an alkylated nucleobase
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:3.2.2.21-RXN
References:
  • Evensen G, Seeberg E (1982). "Adaptation to alkylation resistance involves the induction of a DNA glycosylase." Nature 296(5859);773-5. PMID: 7040984
  • Karran P, Hjelmgren T, Lindahl T (1982). "Induction of a DNA glycosylase for N-methylated purines is part of the adaptive response to alkylating agents." Nature 296(5859);770-3. PMID: 7040983
  • Riazuddin S, Lindahl T (1978). "Properties of 3-methyladenine-DNA glycosylase from Escherichia coli." Biochemistry 17(11);2110-8. PMID: 352392
  • Thomas L, Yang CH, Goldthwait DA (1982). "Two DNA glycosylases in Escherichia coli which release primarily 3-methyladenine." Biochemistry 21(6);1162-9. PMID: 7041972