Reaction 21584

Reaction Details
Reaction: Thumb
pyruvate + D-glyceraldehyde 3-phosphate + H+ → CO2 + 1-deoxy-D-xylulose 5-phosphate
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:DXS-RXN
References:
  • Kuzuyama T, Takagi M, Takahashi S, Seto H (2000). "Cloning and characterization of 1-deoxy-D-xylulose 5-phosphate synthase from Streptomyces sp. Strain CL190, which uses both the mevalonate and nonmevalonate pathways for isopentenyl diphosphate biosynthesis." J Bacteriol 182(4);891-7. PMID: 10648511
  • Sprenger GA, Schorken U, Wiegert T, Grolle S, de Graaf AA, Taylor SV, Begley TP, Bringer-Meyer S, Sahm H (1997). "Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy-D-xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol." Proc Natl Acad Sci U S A 94(24);12857-62. PMID: 9371765