Reaction Details
Reaction: Thumb
2 nitric oxide[out] + 2 a reduced c-type cytochrome[out] + 2 H+[out] → nitrous oxide[out] + 2 an oxidized c-type cytochrome[out] + H2O[out]
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:NITRIC-OXIDE-REDUCTASE-RXN
References:
  • Cheesman MR, Zumft WG, Thomson AJ (1998). "The MCD and EPR of the heme centers of nitric oxide reductase from Pseudomonas stutzeri: evidence that the enzyme is structurally related to the heme-copper oxidases." Biochemistry 37(11);3994-4000. PMID: 9521721
  • Heiss B, Frunzke K, Zumft WG (1989). "Formation of the N-N bond from nitric oxide by a membrane-bound cytochrome bc complex of nitrate-respiring (denitrifying) Pseudomonas stutzeri." J Bacteriol 1989;171(6);3288-97. PMID: 2542222
  • Hendriks J, Warne A, Gohlke U, Haltia T, Ludovici C, Lubben M, Saraste M (1998). "The active site of the bacterial nitric oxide reductase is a dinuclear iron center." Biochemistry 37(38);13102-9. PMID: 9748316
  • Hendriks J, Gohlke U, Saraste M (1998). "From NO to OO: nitric oxide and dioxygen in bacterial respiration." J Bioenerg Biomembr 30(1);15-24. PMID: 9623801
  • Hino T, Matsumoto Y, Nagano S, Sugimoto H, Fukumori Y, Murata T, Iwata S, Shiro Y (2010). "Structural basis of biological N2O generation by bacterial nitric oxide reductase." Science 330(6011);1666-70. PMID: 21109633
  • Kumita H, Matsuura K, Hino T, Takahashi S, Hori H, Fukumori Y, Morishima I, Shiro Y (2004). "NO reduction by nitric-oxide reductase from denitrifying bacterium Pseudomonas aeruginosa: characterization of reaction intermediates that appear in the single turnover cycle." J Biol Chem 279(53);55247-54. PMID: 15504726