Reaction Details
Reaction: Thumb
N-formylkynurenine + H2O → L-kynurenine + formate + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:ARYLFORMAMIDASE-RXN
References:
  • Hayaishi O, Stanier RY (1951). "The bacterial oxidation of tryptophan. III. Enzymatic activities of cell-free extracts from bacteria employing the aromatic pathway." J Bacteriol 62(6);691-709. PMID: 14907621
  • Jakoby WB (1954). "Kynurenine formamidase from Neurospora." J Biol Chem 207(2);657-63. PMID: 13163050
  • Mehler AH, Knox WE (1950). "The conversion of tryptophan to kynurenine in liver. II. The enzymatic hydrolysis of formylkynurenine." J Biol Chem 187(1);431-8. PMID: 14794728