Reaction Details
Reaction: Thumb
hydrogen carbonate + pyruvate + ATP → oxaloacetate + ADP + phosphate + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:PYRUVATE-CARBOXYLASE-RXN
References:
  • McClure WR, Lardy HA, Kneifel HP (1971). "Rat liver pyruvate carboxylase. I. Preparation, properties, and cation specificity." J Biol Chem 246(11);3569-78. PMID: 5578910
  • Scrutton MC, Young MR, Utter MF (1970). "Pyruvate carboxylase from baker's yeast. The presence of bound zinc." J Biol Chem 245(22);6220-7. PMID: 5484476
  • SEUBERT W, REMBERGER U (1961). "[Purification and mechanism of action of pyruvate carboxylase from Pseudomonas citronellolis]." Biochem Z 334;401-14. PMID: 13750403
  • UTTER MF, KEECH DB (1963). "PYRUVATE CARBOXYLASE. I. NATURE OF THE REACTION." J Biol Chem 238;2603-8. PMID: 14063279