Reaction Details
Reaction: Thumb
2,5-dioxopentanoate + NADP+ + H2O → 2-oxoglutarate + NADPH + 2 H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:25-DIOXOVALERATE-DEHYDROGENASE-RXN
References:
  • Adams E, Rosso G (1967). "Alpha-ketoglutaric semialdehyde dehydrogenase of Pseudomonas. Properties of the purified enzyme induced by hydroxyproline and of the glucarate-induced and constitutive enzymes." J Biol Chem 242(8);1802-14. PMID: 6024771