Reaction Details
Reaction: Thumb
2-amino-4-deoxyisochorismate → 2,3-dihydro-3-hydroxyanthranilate + pyruvate
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:RXNB-5654
References:
  • Mavrodi DV, Bonsall RF, Delaney SM, Soule MJ, Phillips G, Thomashow LS (2001). "Functional analysis of genes for biosynthesis of pyocyanin and phenazine-1-carboxamide from Pseudomonas aeruginosa PAO1." J Bacteriol 183(21);6454-65. PMID: 11591691
  • Parsons JF, Calabrese K, Eisenstein E, Ladner JE (2003). "Structure and mechanism of Pseudomonas aeruginosa PhzD, an isochorismatase from the phenazine biosynthetic pathway." Biochemistry 42(19);5684-93. PMID: 12741825