Reaction 21056

Reaction Details
Reaction: Thumb
(S)-3-hydroxy-3-methylglutaryl-CoA ↔ acetoacetate + acetyl-CoA
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN
References:
  • Bachhawat, B.K., Robinson, W.G., Coon, M.J. (1955). "The enzymatic cleavage of beta-hydroxy-beta-methylglutaryl coenzyme A to acetoacetate and acetyl coenzyme A." J Biol Chem 216(2);727-36. PMID: 13271348