P. aeruginosa Metabolome Database Protein PA5140

Identification

Name:

imidazoleglycerol-phosphate synthase, cyclase subunit

Synonyms:

Not Available

Gene Name:

hisF1

Enzyme Class:

Not Available

Biological Properties

General Function:

histidine biosynthetic process, metabolic process

Specific Function:

imidazoleglycerol-phosphate synthase activity, catalytic activity

Cellular Location:

Cytoplasmic

KEGG Pathways:

superpathway of histidine, purine, and pyrimidine biosynthesis PRPP-PWY
L-histidine biosynthesis HISTSYN-PWY

KEGG Reactions:

Not Available

SMPDB Reactions:

Not Available

PseudoCyc/BioCyc Reactions:

phosphoribulosylformimino-AICAR-P + L-glutamine → L-glutamate + D-erythro-imidazole-glycerol-phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + H⁺
ReactionCard

Complex Reactions:

Not Available

Transports:

Not Available

Metabolites:

Not Available

GO Classification:

Component
imidazoleglycerol-phosphate synthase complex
Function
imidazoleglycerol-phosphate synthase activity
catalytic activity
Process
histidine biosynthetic process
metabolic process

Gene Properties

Locus tag:

PA5140

Strand:

Entrez Gene ID:

878541

Accession:

NP_253827.1

GI:

15600333

Sequence start:

5788614

Sequence End:

5789384

Sequence Length:

770

Gene Sequence:

>PA5140
ATGGCACTGGCAAAACGCATCATCCCCTGCCTCGACGTGGACAACGGCCGAGTGGTCAAGGGCGTCAAGTTCGAGAACATCCGCGACGCCGGCGACCCGGTCGAGATCGCTCGCCGCTACGACGAGCAGGGTGCCGACGAGATCACCTTCCTCGATATCACCGCCAGCGTCGACGGGCGCGACACCACCCTGCATACCGTCGAGCGCATGGCTAGCCAGGTGTTCATTCCGCTGACCGTGGGCGGCGGCGTACGCAGCGTGCAGGACATCCGCAACCTGTTGAATGCCGGCGCGGACAAGGTCTCGATCAACACCGCCGCGGTGTTCAACCCCGAGTTCGTCGGTGAGGCCGCCGACCGCTTCGGCTCGCAGTGCATCGTGGTCGCCATCGACGCGAAGAAGGTTTCCGCCCCGGGCGAGGCGCCGCGCTGGGAAATCTTCACCCATGGCGGGCGCAAGCCCACCGGGCTGGATGCCGTGCTCTGGGCGAAGAAGATGGAAGACTTGGGCGCTGGCGAGATTCTCCTGACCAGCATGGACCAGGACGGCGTGAAGAGCGGTTACGACCTGGGCGTGACCCGCGCCATCAGCGAGGCGGTGAACGTGCCGGTGATCGCTTCCGGCGGCGTCGGCAACCTGGAGCACCTGGCCGCCGGCATCCTCGAGGGCAAGGCCGACGCGGTGCTCGCGGCGAGCATCTTCCACTTCGGCGAGTACACCGTGCCGGAAGCCAAGGCCTACCTGGCCAGCCGCGGTATCGTGGTGCGCTGA

Protein Properties

Protein Residues:

256

Protein Molecular Weight:

27.1 kDa

Protein Theoretical pI:

4.88

Hydropathicity (GRAVY score):

0.067

Charge at pH 7 (predicted):

-7.09

Protein Sequence:

>PA5140
MALAKRIIPCLDVDNGRVVKGVKFENIRDAGDPVEIARRYDEQGADEITFLDITASVDGRDTTLHTVERMASQVFIPLTVGGGVRSVQDIRNLLNAGADKVSINTAAVFNPEFVGEAADRFGSQCIVVAIDAKKVSAPGEAPRWEIFTHGGRKPTGLDAVLWAKKMEDLGAGEILLTSMDQDGVKSGYDLGVTRAISEAVNVPVIASGGVGNLEHLAAGILEGKADAVLAASIFHFGEYTVPEAKAYLASRGIVVR

References

External Links:

Resource	Link
Genome ID:	PA5140
Entrez Gene ID:	878541
NCBI Protein ID:	15600333

General Reference:

PaperBLAST - Find papers about PA5140 and its homologs

imidazoleglycerol-phosphate synthase, cyclase subunit (PA5140)