Identification
Name: lactoylglutathione lyase aldoketomutase, methylglyoxalase; glyoxalase I
Synonyms: glo1
Gene Name: gloA3
Enzyme Class: Not Available
Biological Properties
General Function: pyruvate metabolic process, methylglyoxal catabolic process to D-lactate
Specific Function: O-acetylhomoserine aminocarboxypropyltransferase activity, zinc ion binding, lactoylglutathione lyase activity
Cellular Location: Cytoplasmic
KEGG Pathways:
KEGG Reactions: Not Available
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb
(R)-S-lactoylglutathione = methylglyoxal + glutathione
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites: Not Available
GO Classification:
Function
O-acetylhomoserine aminocarboxypropyltransferase activity
zinc ion binding
lactoylglutathione lyase activity
Process
pyruvate metabolic process
methylglyoxal catabolic process to D-lactate
Gene Properties
Locus tag: PA5111
Strand: -
Entrez Gene ID: 882241
Accession: NP_253798.1
GI: 15600304
Sequence start: 5753614
Sequence End: 5754144
Sequence Length: 530
Gene Sequence:
>PA5111
ATGAGTTTCAACACCGAAGTACAGCCCGGCATCTGCATGGAGCCGGACGCCATCACCCAGGAATACGTGTTCAACCACACCATGTTGCGGGTCAAGGATCCGAAGCGCTCGCTCGACTTCTACTCGCGGGTGCTCGGCATGCGCCTGCTGCGTCGCCTGGATTTCGAGGAAGGCCGCTTCTCCCTGTATTTCCTCGCCATGACCCGTGGCGAAGAAGTGCCTGATGCGGTTGACGAGCGCCAGCGATATACCTTCGGACGCCAGTCGGTCCTCGAGCTGACCCACAACTGGGGCAGCGAGAGCGACGACAGCCAGTACCACAACGGCAACCAGGACCCGCGCGGGTTCGGCCACATCTGCTTCTCGGTGCCCGACCTGGTGGCGGCCTGCGAGCGTTTCGAGACGCTCGGGGTGAACTTCGTCAAGCCGCTGGACCGAGGCATGAAGAACGTGGCCTTCATCAGCGATCCCGACGGCTACTGGGTGGAAATCGTCCAGGCCAGCCTGAACGGCGAGATGGGACGCGGCTGA
Protein Properties
Protein Residues: 176
Protein Molecular Weight: 20.2 kDa
Protein Theoretical pI: 4.77
Hydropathicity (GRAVY score): -0.474
Charge at pH 7 (predicted): -7.13
Protein Sequence:
>PA5111
MSFNTEVQPGICMEPDAITQEYVFNHTMLRVKDPKRSLDFYSRVLGMRLLRRLDFEEGRFSLYFLAMTRGEEVPDAVDERQRYTFGRQSVLELTHNWGSESDDSQYHNGNQDPRGFGHICFSVPDLVAACERFETLGVNFVKPLDRGMKNVAFISDPDGYWVEIVQASLNGEMGRG
References
External Links:
Resource Link
Genome ID: PA5111
Entrez Gene ID: 882241
NCBI Protein ID: 15600304
General Reference: PaperBLAST - Find papers about PA5111 and its homologs