Identification
Name: nicotinate phosphoribosyltransferase
Synonyms: Not Available
Gene Name: pncB2
Enzyme Class: Not Available
Biological Properties
General Function: cofactor biosynthetic process, NAD biosynthetic process
Specific Function: nicotinate phosphoribosyltransferase activity, nicotinate-nucleotide diphosphorylase (carboxylating) activity
Cellular Location: Cytoplasmic
KEGG Pathways:
KEGG Reactions: Not Available
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb
nicotinate + 5-phospho-α-D-ribose 1-diphosphate + ATP + H2O → β-nicotinate D-ribonucleotide + ADP + diphosphate + phosphate
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites: Not Available
GO Classification:
Function
nicotinate phosphoribosyltransferase activity
nicotinate-nucleotide diphosphorylase (carboxylating) activity
Process
cofactor biosynthetic process
NAD biosynthetic process
Gene Properties
Locus tag: PA4376
Strand: +
Entrez Gene ID: 881378
Accession: NP_253066.1
GI: 15599572
Sequence start: 4907841
Sequence End: 4909037
Sequence Length: 1196
Gene Sequence:
>PA4376
ATGGCCGAGAGCGCTTTTTCCGAACGTATCGTGCAGAACCTGCTGGATACCGACTTCTACAAGCTGACCATGATGCAGGCGGTGCTGCACAACTATCCCAACGCCGAGGTGGAATGGGAGTTCCGCTGCCGCAACCAGGAAGACCTGCGCCTGTACCTGCCGGCCATCCGCGAACAACTGGAATACCTGGCGGGCCTGGCGATCAGCGACGAGCAACTGGCCTTCCTCGAACGGATTCCCTTCCTCGCGCCGGACTTCATCCGCTTCCTCGGGTTGTTCCGCTTCAACCCGCGCTACGTGCAGACCGGCATCGAGAACGACGAATTCTTCCTGCGCCTGAAAGGTCCCTGGCTGCACGTGATCCTCTTCGAAGTGCCGCTGCTGGCGATGATCAGCGAGGTGCGCAACCGCGCCCGCTACCCGGCCGCCACCGTCGAGCAGGCGCGCGAACGCCTGCAGGAAAAGTTCGATTGGCTGCGCCGGGAGGCCAGCGCCGAGGAACTGGCCGGCTTCAAGATGGCCGACTTCGGTACCCGCCGCCGCTTCTCCTATCGGGTCCACGAGGCGGTGGTGAGCGGTCTGAAGGAGGACTTTCCGGGCTGCTTCGTCGGCACCAGCAACGTCCACCTGGCACGCAAGCTCGACCTCAAGCCCCTCGGCACCATGGCCCACGAATGGCTGATGGCCCACCAGCAGCTCGGTCCGCGCCTGATCGACAGCCAGAGTGCCGCGTTGGACTGCTGGGTCCGCGAATACCGTGGGCTGCTCGGCATCGCGCTGACCGACTGCATCACCACCGATGCCTTCCTGCGCGACTTCGACCTCTATTTCGCCAAGCTCTTCGACGGCCTCCGCCACGACTCGGGCGACCCATTGCTGTGGGCGGAAAAGACCATCGCCCACTACCTCAAGCTGGGCATCGACCCGCTGACCAAGACCCTGGTGTTCTCCGACGGCCTCGACCTGCCGCGGGCCCTGAAGATCTATCGCGCGCTGCAGGGCCGGATCAACGTCAGCTTCGGCATAGGCACGCATTTCACCTGCGACCTGCCGGGCGTCGAGCCGATGAACATCGTGGTGAAGATGAGCGCCTGCAACGGCCATCCGGTGGCGAAGATCTCCGATACGCCCGGCAAGGCGCAATGCCGGGACCCTGACTTCATCCACTACCTCAAGCACGTGTTCCAGGTCGCCTAG
Protein Properties
Protein Residues: 398
Protein Molecular Weight: 45.7 kDa
Protein Theoretical pI: 6.65
Hydropathicity (GRAVY score): -0.113
Charge at pH 7 (predicted): -2.31
Protein Sequence:
>PA4376
MAESAFSERIVQNLLDTDFYKLTMMQAVLHNYPNAEVEWEFRCRNQEDLRLYLPAIREQLEYLAGLAISDEQLAFLERIPFLAPDFIRFLGLFRFNPRYVQTGIENDEFFLRLKGPWLHVILFEVPLLAMISEVRNRARYPAATVEQARERLQEKFDWLRREASAEELAGFKMADFGTRRRFSYRVHEAVVSGLKEDFPGCFVGTSNVHLARKLDLKPLGTMAHEWLMAHQQLGPRLIDSQSAALDCWVREYRGLLGIALTDCITTDAFLRDFDLYFAKLFDGLRHDSGDPLLWAEKTIAHYLKLGIDPLTKTLVFSDGLDLPRALKIYRALQGRINVSFGIGTHFTCDLPGVEPMNIVVKMSACNGHPVAKISDTPGKAQCRDPDFIHYLKHVFQVA
References
External Links:
Resource Link
Genome ID: PA4376
Entrez Gene ID: 881378
NCBI Protein ID: 15599572
General Reference: PaperBLAST - Find papers about PA4376 and its homologs