homoserine dehydrogenase (PA3736)

Identification
Name: homoserine dehydrogenase
Synonyms: Not Available
Gene Name: hom
Enzyme Class: Not Available
Biological Properties
General Function: threonine biosynthetic process, cellular amino acid metabolic process, oxidation-reduction process, metabolic process
Specific Function: homoserine dehydrogenase activity, oxidoreductase activity, NADP binding, amino acid binding
Cellular Location: Cytoplasmic
KEGG Pathways:
  • superpathway of L-threonine biosynthesis THRESYN-PWY
  • superpathway of L-lysine, L-threonine and L-methionine biosynthesis I P4-PWY
  • L-homoserine biosynthesis HOMOSERSYN-PWY
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    L-homoserine + NAD(P)+ ← L-aspartate-semialdehyde + NAD(P)H + H+
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    homoserine dehydrogenase activity
    oxidoreductase activity
    NADP binding
    amino acid binding
    Process
    threonine biosynthetic process
    cellular amino acid metabolic process
    oxidation-reduction process
    metabolic process
    Gene Properties
    Locus tag: PA3736
    Strand: -
    Entrez Gene ID: 880337
    Accession: NP_252425.1
    GI: 15598931
    Sequence start: 4188243
    Sequence End: 4189547
    Sequence Length: 1304
    Gene Sequence: 
    >PA3736
GTGAAACCGGTCAAAGTAGGCATCTGTGGGTTGGGGACCGTCGGTGGCGGTACCTTCAATGTACTCGAACGCAACGCCGAGGAGATTGCCCGCCGTGCCGGGCGCGGTATCGAGGTTGCGCAGATCGCCGCCCGCCGGCCGAACCCGAAGTGCGATACCGGTGCGACCCCCATCACCGCCGATATCTTCGACGTAGCGTGCAATCCCGAGATCGACGTGGTCGTCGAGTTGATCGGCGGCTACACCCTGGCCCACGAGCTGGTGCTCAAGGCCATCGAGAACGGCAAGCACGTGGTCACCGCGAACAAGGCGCTGATCGCCGTGCACGGCAACGAGATCTTCGCCAAGGCCCGCGAGAAGGGCGTGATCGTCGCCTTCGAGGCCGCTGTCGCCGGCGGCATCCCGGTGATCAAGGCGATCCGCGAGGGGCTGTCGGCCAACCGCATCAACTGGCTGGCCGGGATCATCAACGGTACCGGCAACTTCATCCTCAGCGAAATGCGCGAGAAGGGCCGTACCTTCCCCGACGTGCTCGCCGAGGCCCAGGCCCTGGGCTATGCCGAGGCCGACCCGACCTTCGACGTGGAAGGCATCGACGCCGCCCACAAGCTGACCATCCTCGCCTCGATCGCCTTCGGCATTCCGCTGCAGTTCGACAAGGCCTACACCGAAGGCATCTCGAAACTGACCAGCGCCGACGTCAACTACGCCGACGCCCTCGGCTATCGCATCAAGCACCTGGGCGTGGCGCGTCGCACCGAGAGCGGCTTCGAGCTGCGCGTGCACCCGACCCTGATTCCCTCGGATCGCCTGATCGCCAACGTCAACGGCGTGATGAACGCGGTGATGGTCAACGGCGACGCCGTCGGCTCGACCCTCTACTACGGCGCCGGTGCCGGAATGGAGCCGACCGCTTCCTCGGTGGTGGCCGACCTCGTCGACGTGGTCCGCGCCATGACCTCCGATCCGGAGAACCGCGTACCGCACCTGGCGTTCCAGCCGGACGCGCTGTCCGACCACCCGATCCTGCCGATCGAAGCCTGCGAAAGCGCCTACTACCTGCGCATCCAGGCCAAGGACCACCCGGGCGTACTGGCCCAGGTGGCCACCATCCTGTCCGAGCGCGGCATCAACATCGAATCGATCATGCAGAAGGAGGCCGAGGAACAGGACGGCCTGGTGCCGATGATCCTGGTTACCCACCGGGTCATCGAACAACGCATCAACGATGCCATCGCCGCCCTGGAAGCGCTGGAAGGCGTGTCCGGGCCGGTGGTCCGCATCCGTGTCGAACAACTGAATTGA
    Protein Properties
    Protein Residues: 434
    Protein Molecular Weight: 46.2 kDa
    Protein Theoretical pI: 5.09
    Hydropathicity (GRAVY score): 0.135
    Charge at pH 7 (predicted): -11.7
    Protein Sequence: 
    >PA3736
MKPVKVGICGLGTVGGGTFNVLERNAEEIARRAGRGIEVAQIAARRPNPKCDTGATPITADIFDVACNPEIDVVVELIGGYTLAHELVLKAIENGKHVVTANKALIAVHGNEIFAKAREKGVIVAFEAAVAGGIPVIKAIREGLSANRINWLAGIINGTGNFILSEMREKGRTFPDVLAEAQALGYAEADPTFDVEGIDAAHKLTILASIAFGIPLQFDKAYTEGISKLTSADVNYADALGYRIKHLGVARRTESGFELRVHPTLIPSDRLIANVNGVMNAVMVNGDAVGSTLYYGAGAGMEPTASSVVADLVDVVRAMTSDPENRVPHLAFQPDALSDHPILPIEACESAYYLRIQAKDHPGVLAQVATILSERGINIESIMQKEAEEQDGLVPMILVTHRVIEQRINDAIAALEALEGVSGPVVRIRVEQLN
    References
    External Links:
    Resource Link
    Genome ID: PA3736
    Entrez Gene ID: 880337
    NCBI Protein ID: 15598931
    General Reference: PaperBLAST - Find papers about PA3736 and its homologs