Phosphogluconate dehydratase (PA3194)

Identification
Name: Phosphogluconate dehydratase
Synonyms:
  • 6-phosphogluconate dehydratase
Gene Name: edd
Enzyme Class:
Biological Properties
General Function: Involved in phosphogluconate dehydratase activity
Specific Function: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6- phospho-D-gluconate + H(2)O
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb ↔ Thumb+Thumb
6-Phosphogluconic acid ↔ 2-Keto-3-deoxy-6-phosphogluconic acid + Water
ReactionCard
SMPDB Reactions:
gluconate 6-phosphate → Thumb+Thumb
gluconate 6-phosphate → Water + 2-Keto-3-deoxy-6-phosphogluconic acid
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb ↔ Thumb+Thumb
6-Phosphogluconic acid ↔ 2-Keto-3-deoxy-6-phosphogluconic acid + Water
ReactionCard
Complex Reactions:
Thumb → Thumb+Thumb
6-Phosphogluconic acid → 2-Keto-3-deoxy-6-phosphogluconic acid + Water
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0003632-Keto-3-deoxy-6-phosphogluconic acidMetaboCard
PAMDB0003366-Phosphogluconic acidMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
carbon-oxygen lyase activity
catalytic activity
hydro-lyase activity
lyase activity
phosphogluconate dehydratase activity
Process
carbohydrate metabolic process
cellular carbohydrate metabolic process
Entner-Doudoroff pathway
metabolic process
primary metabolic process
Gene Properties
Locus tag: PA3194
Strand: -
Entrez Gene ID: 882909
Accession: NP_251884.1
GI: 15598390
Sequence start: 3585477
Sequence End: 3587303
Sequence Length: 1826
Gene Sequence: 
>PA3194
ATGCACCCTCGTGTGCTCGAAGTCACCCGCCGCATCCAGGCCCGTAGCGCGGCCACTCGCCAGCGCTACCTCGAGATGGTCCGGGCTGCGGCCAGCAAGGGGCCGCACCGCGGCACCCTGCCGTGCGGCAACCTCGCCCACGGGGTCGCGGCCTGTGGCGAAAGCGACAAGCAGACCCTGCGGCTGATGAACCAGGCCAACGTGGCCATCGTTTCCGCCTACAACGACATGCTCTCGGCGCACCAGCCGTTCGAGCGCTTTCCGGGGCTGATCAAGCAGGCGCTGCACGAGATCGGTTCGGTCGGCCAGTTCGCCGGCGGCGTGCCGGCCATGTGCGACGGGGTGACCCAGGGCGAGCCGGGCATGGAACTGTCGCTGGCCAGCCGCGACGTGATCGCCATGTCCACCGCCATCGCGCTGTCTCACAACATGTTCGATGCAGCGCTGTGCCTGGGTGTTTGCGACAAGATCGTGCCGGGCCTGCTGATCGGCTCGCTGCGCTTCGGCCACCTGCCCACCGTGTTCGTCCCGGCCGGGCCGATGCCGACCGGCATCTCCAACAAGGAAAAGGCCGCGGTGCGCCAACTGTTCGCCGAAGGCAAGGCCACTCGCGAAGAGCTGCTGGCCTCGGAAATGGCCTCCTACCATGCACCCGGCACCTGCACCTTCTATGGCACCGCCAATACCAACCAGTTGCTGGTGGAGGTGATGGGCCTGCACTTGCCCGGTGCCTCCTTCGTCAACCCGAACACCCCCCTGCGCGACGAACTCACCCGCGAAGCGGCACGCCAGGCCAGCCGGCTGACCCCCGAGAACGGCAACTACGTGCCGATGGCGGAGATCGTCGACGAGAAGGCCATCGTCAACTCGGTGGTGGCGCTGCTCGCCACCGGCGGCTCGACCAACCACACCCTGCACCTGCTGGCGATCGCCCAGGCGGCGGGCATCCAGTTGACCTGGCAGGACATGTCCGAGCTGTCCCATGTGGTGCCGACCCTGGCGCGCATCTATCCGAACGGCCAGGCCGACATCAACCACTTCCAGGCGGCCGGCGGCATGTCCTTCCTGATCCGCCAACTGCTCGACGGCGGGCTGCTTCACGAGGACGTACAGACCGTCGCCGGCCCCGGCCTGCGCCGCTACACCCGCGAGCCGTTCCTCGAGGATGGCCGGCTGGTCTGGCGCGAAGGGCCGGAACGGAGTCTCGACGAAGCCATCCTGCGTCCGCTGGACAAGCCGTTCTCCGCCGAAGGCGGCTTGCGCCTGATGGAGGGCAACCTCGGTCGCGGCGTGATGAAGGTCTCGGCGGTGGCGCCGGAACACCAGGTGGTCGAGGCGCCGGTACGGATCTTCCACGACCAGGCCAGCCTGGCCGCGGCCTTCAAGGCCGGCGAGCTGGAGCGCGACCTGGTCGCCGTGGTGCGTTTCCAGGGCCCGCGGGCGAACGGCATGCCGGAGCTGCACAAGCTCACGCCGTTCCTCGGGGTCCTGCAGGATCGTGGCTTCAAGGTGGCGCTGGTCACCGACGGGCGCATGTCCGGGGCGTCGGGCAAGGTGCCCGCGGCCATCCATGTGAGTCCGGAAGCCATCGCCGGCGGTCCGCTGGCGCGCCTGCGCGACGGCGACCGGGTGCGGGTGGATGGGGTGAACGGCGAGTTGCGGGTGCTGGTCGACGACGCCGAATGGCAGGCGCGCAGCCTGGAGCCGGCGCCGCAGGACGGCAATCTCGGTTGCGGCCGCGAGCTGTTCGCCTTCATGCGCAACGCCATGAGCAGCGCGGAAGAGGGCGCCTGCAGCTTTACCGAGAGCCTCAACGGCTGGCGCTGA
Protein Properties
Protein Residues: 608
Protein Molecular Weight: 65.2 kDa
Protein Theoretical pI: 6.7
Hydropathicity (GRAVY score): -0.079
Charge at pH 7 (predicted): -2.88
Protein Sequence: 
>PA3194
MHPRVLEVTRRIQARSAATRQRYLEMVRAAASKGPHRGTLPCGNLAHGVAACGESDKQTLRLMNQANVAIVSAYNDMLSAHQPFERFPGLIKQALHEIGSVGQFAGGVPAMCDGVTQGEPGMELSLASRDVIAMSTAIALSHNMFDAALCLGVCDKIVPGLLIGSLRFGHLPTVFVPAGPMPTGISNKEKAAVRQLFAEGKATREELLASEMASYHAPGTCTFYGTANTNQLLVEVMGLHLPGASFVNPNTPLRDELTREAARQASRLTPENGNYVPMAEIVDEKAIVNSVVALLATGGSTNHTLHLLAIAQAAGIQLTWQDMSELSHVVPTLARIYPNGQADINHFQAAGGMSFLIRQLLDGGLLHEDVQTVAGPGLRRYTREPFLEDGRLVWREGPERSLDEAILRPLDKPFSAEGGLRLMEGNLGRGVMKVSAVAPEHQVVEAPVRIFHDQASLAAAFKAGELERDLVAVVRFQGPRANGMPELHKLTPFLGVLQDRGFKVALVTDGRMSGASGKVPAAIHVSPEAIAGGPLARLRDGDRVRVDGVNGELRVLVDDAEWQARSLEPAPQDGNLGCGRELFAFMRNAMSSAEEGACSFTESLNGWR
References
External Links:
Resource Link
Genome ID: PA3194
Entrez Gene ID: 882909
NCBI Protein ID: 15598390
General Reference: PaperBLAST - Find papers about PA3194 and its homologs