imidazoleglycerol-phosphate synthase, cyclase subunit (PA3151)

Identification
Name: imidazoleglycerol-phosphate synthase, cyclase subunit
Synonyms: Not Available
Gene Name: hisF2
Enzyme Class: Not Available
Biological Properties
General Function: cellular amino acid metabolic process, histidine metabolic process, histidine biosynthetic process, metabolic process, O antigen biosynthetic process
Specific Function: catalytic activity, oxo-acid-lyase activity
Cellular Location: Cytoplasmic
KEGG Pathways:
  • superpathway of histidine, purine, and pyrimidine biosynthesis PRPP-PWY
  • L-histidine biosynthesis HISTSYN-PWY
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    phosphoribulosylformimino-AICAR-P + L-glutamine → L-glutamate + D-erythro-imidazole-glycerol-phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + H+
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    catalytic activity
    oxo-acid-lyase activity
    Process
    cellular amino acid metabolic process
    histidine metabolic process
    histidine biosynthetic process
    metabolic process
    O antigen biosynthetic process
    Gene Properties
    Locus tag: PA3151
    Strand: -
    Entrez Gene ID: 882582
    Accession: NP_251841.1
    GI: 15598347
    Sequence start: 3535216
    Sequence End: 3535971
    Sequence Length: 755
    Gene Sequence: 
    >PA3151
ATGGTCCGGAGGCGCGTTATCCCATGCTTGCTGCTCAAGGATCGCGGTCTAGTGAAAACCGTGAAGTTCAAGGAGCCCAAGTACGTTGGAGACCCGATCAACGCAATACGCATCTTCAATGAGAAAGAAGTCGACGAACTGATTTTGCTGGATATAGATGCTTCCAGGCTCAATCAAGAGCCTAACTATGAGTTGATCGCGGAAGTGGCTGGTGAGTGTTTTATGCCTATTTGCTATGGGGGCGGTATCAAGACATTGGAGCATGCGGAAAAAATCTTTTCCCTAGGTGTCGAAAAAGTTTCGATAAATACCGCCGCTCTTATGGATCTTTCGTTGATTCGAAGAATTGCCGATAAGTTTGGTTCGCAAAGCGTAGTTGGCTCTATCGACTGCCGCAAGGGTTTCTGGGGAGGACACTCCGTGTTCTCAGAGAATGGGACGCGCGACATGAAACGCTCCCCATTGGAGTGGGCGCAAGCGCTCGAAGAGGCTGGAGTGGGTGAGATTTTTCTAAATTCTATTGATCGAGATGGAGTGCAGAAAGGCTTCGACAACGCTCTAGTGGAAAATATCGCTTCTAACGTCCATGTGCCAGTGATCGCCTGTGGTGGAGCTGGCTCCATCGCTGACCTCATCGATCTTTTTGAGCGTACGTGTGTGTCGGCAGTAGCGGCGGGAAGCCTATTCGTTTTCCATGGCAAGCATCGTGCGGTACTGATTAGTTATCCGGATGTCAACAAGCTCGACGTCGGTTAG
    Protein Properties
    Protein Residues: 251
    Protein Molecular Weight: 27.4 kDa
    Protein Theoretical pI: 5.7
    Hydropathicity (GRAVY score): 0.082
    Charge at pH 7 (predicted): -3.98
    Protein Sequence: 
    >PA3151
MVRRRVIPCLLLKDRGLVKTVKFKEPKYVGDPINAIRIFNEKEVDELILLDIDASRLNQEPNYELIAEVAGECFMPICYGGGIKTLEHAEKIFSLGVEKVSINTAALMDLSLIRRIADKFGSQSVVGSIDCRKGFWGGHSVFSENGTRDMKRSPLEWAQALEEAGVGEIFLNSIDRDGVQKGFDNALVENIASNVHVPVIACGGAGSIADLIDLFERTCVSAVAAGSLFVFHGKHRAVLISYPDVNKLDVG
    References
    External Links:
    Resource Link
    Genome ID: PA3151
    Entrez Gene ID: 882582
    NCBI Protein ID: 15598347
    General Reference: PaperBLAST - Find papers about PA3151 and its homologs