Identification
Name: Protease 3
Synonyms:
  • Pitrilysin
  • Protease III
  • Protease pi
Gene Name: ptrA
Enzyme Class:
Biological Properties
General Function: Involved in catalytic activity
Specific Function: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin
Cellular Location: Periplasm
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb+General-Protein-Substrates ? Peptides
    Water + General-Protein-Substrates ? Peptides
    ReactionCard
    Thumb+General-Protein-Substrates ? Peptides+Peptides
    Water + General-Protein-Substrates ? Peptides + Peptides
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites:
    PAMDB IDNameView
    PAMDB000142WaterMetaboCard
    GO Classification:
    Function
    binding
    catalytic activity
    cation binding
    endopeptidase activity
    hydrolase activity
    ion binding
    metal ion binding
    metalloendopeptidase activity
    peptidase activity
    peptidase activity, acting on L-amino acid peptides
    transition metal ion binding
    zinc ion binding
    Process
    macromolecule metabolic process
    metabolic process
    protein metabolic process
    proteolysis
    Gene Properties
    Locus tag: PA2808
    Strand: -
    Entrez Gene ID: 878671
    Accession: NP_251498.1
    GI: 15598004
    Sequence start: 3162388
    Sequence End: 3162579
    Sequence Length: 191
    Gene Sequence:
    >PA2808
    ATGCGTACCTTCACTGCCTCCACCCTCGCTTTCCTGCTGGTCCTCGCCCCGACCGTTCCGGCCATGGCCGACAGCGGCGGCGACATCGTCTTCGAGCGCATGCAGGCCCAGGCCGCCAAGGCTCGTGCCGCGCACCAGGAGAAACTGGCGAAGCAGGCCGAAGCGACGAAGAAGGACAAGGAAAACTGCTGA
    Protein Properties
    Protein Residues: 63
    Protein Molecular Weight: 6.8 kDa
    Protein Theoretical pI: 9.41
    Hydropathicity (GRAVY score): -0.211
    Charge at pH 7 (predicted): 2.19
    Protein Sequence:
    >PA2808
    MRTFTASTLAFLLVLAPTVPAMADSGGDIVFERMQAQAAKARAAHQEKLAKQAEATKKDKENC
    References
    External Links:
    Resource Link
    Genome ID: PA2808
    Entrez Gene ID: 878671
    NCBI Protein ID: 15598004
    General Reference: PaperBLAST - Find papers about PA2808 and its homologs