Identification
Name: NirE
Synonyms: nirE
Gene Name: nirE
Enzyme Class: Not Available
Biological Properties
General Function: oxidation-reduction process, porphyrin-containing compound biosynthetic process, metabolic process, coenzyme biosynthetic process, anaerobic respiration, heme biosynthetic process
Specific Function: precorrin-2 dehydrogenase activity, methyltransferase activity, methyltransferase activity
Cellular Location: Cytoplasmic
KEGG Pathways:
  • adenosylcobalamin biosynthesis II (late cobalt incorporation) P381-PWY
  • cob(II)yrinate a,c-diamide biosynthesis II (late cobalt incorporation) PWY-7376
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    S-adenosyl-L-methionine + uroporphyrinogen-III → S-adenosyl-L-homocysteine + precorrin-1 + H+
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    precorrin-2 dehydrogenase activity
    methyltransferase activity
    methyltransferase activity
    Process
    oxidation-reduction process
    porphyrin-containing compound biosynthetic process
    metabolic process
    coenzyme biosynthetic process
    anaerobic respiration
    heme biosynthetic process
    Gene Properties
    Locus tag: PA0510
    Strand: -
    Entrez Gene ID: 881871
    Accession: NP_249201.1
    GI: 15595707
    Sequence start: 572583
    Sequence End: 573422
    Sequence Length: 839
    Gene Sequence:
    >PA0510
    ATGAACACTACCGTGATTCCGCCGTCCCTCCTCGATGTCGATTTCCCTGCCGGCAGCGTCGCCCTGGTCGGCGCCGGCCCCGGCGATCCGGGCCTGCTCACCCTGCGCGCCTGGGCCCTGCTGCAACAGGCCGAGGTGGTGGTCTACGACCGCCTGGTCGCCCGCGAGCTGATCGCCCTTCTGCCGGAAAGCTGCCAGCGCATCTACGTCGGCAAGCGCTGCGGCCACCACAGCCTGCCGCAGGAAGAAATCAACGAGCTGCTGGTGCGCCTGGCCCGGCAGCAACGCCGGGTGGTCCGCCTGAAAGGCGGCGACCCGTTCATCTTCGGTCGCGGCGCCGAGGAGCTGGAGCGCCTGCTCGAAGCCGGCGTCGACTGCCAGGTGGTCCCCGGCGTCACCGCCGCCTCCGGTTGCAGTACCTACGCCGGCATCCCGCTGACCCACCGCGACCTCGCCCAGTCCTGCACCTTCGTCACCGGCCACCTGCAGAACGACGGCCGCCTCGACCTCGACTGGGCCGGCCTGGCGCGTGGCAAGCAGACCCTGGTGTTCTACATGGGCCTGGGCAACCTCGCCGAGATCGCCGCGCGCCTGGTCGAGCACGGCCTCGCCAGCGACACCCCGGCGGCGCTGGTCAGCCAGGGCACCCAGGCGGGCCAGCAGGTGACCCGCGGCGCCCTTGCCGAGCTGCCGGCGCTGGCGCGACGCTACCAGTTGAAGCCGCCGACGCTGATCGTCGTCGGCCAGGTGGTCGCGCTCTTCGCCGAGCGCGCGATGGCGCATCCGTCATACCTGGGCGCCGGCTCGCCGGTCAGCCGCGAGGCCGTCGCATGCGCCTGA
    Protein Properties
    Protein Residues: 279
    Protein Molecular Weight: 29.7 kDa
    Protein Theoretical pI: 7.09
    Hydropathicity (GRAVY score): 0.159
    Charge at pH 7 (predicted): 0.26
    Protein Sequence:
    >PA0510
    MNTTVIPPSLLDVDFPAGSVALVGAGPGDPGLLTLRAWALLQQAEVVVYDRLVARELIALLPESCQRIYVGKRCGHHSLPQEEINELLVRLARQQRRVVRLKGGDPFIFGRGAEELERLLEAGVDCQVVPGVTAASGCSTYAGIPLTHRDLAQSCTFVTGHLQNDGRLDLDWAGLARGKQTLVFYMGLGNLAEIAARLVEHGLASDTPAALVSQGTQAGQQVTRGALAELPALARRYQLKPPTLIVVGQVVALFAERAMAHPSYLGAGSPVSREAVACA
    References
    External Links:
    Resource Link
    Genome ID: PA0510
    Entrez Gene ID: 881871
    NCBI Protein ID: 15595707
    General Reference: PaperBLAST - Find papers about PA0510 and its homologs