Identification
Name: Alkyl hydroperoxide reductase subunit C
Synonyms:
  • Alkyl hydroperoxide reductase protein C22
  • Peroxiredoxin
  • SCRP-23
  • Sulfate starvation-induced protein 8
  • SSI8
  • Thioredoxin peroxidase
Gene Name: ahpC
Enzyme Class:
Biological Properties
General Function: Involved in peroxiredoxin activity
Specific Function: Directly reduces organic hydroperoxides in its reduced dithiol form
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
2 Thiol-containing reductant+ROOHOxidized thiol-containing reductant+Thumb+ROH
2 Thiol-containing reductant + ROOH ↔ Oxidized thiol-containing reductant + Water + ROH
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
2 R'-SH+ROOHR'-S-S-R'+Thumb+ROH
2 R'-SH + ROOH → R'-S-S-R' + Water + ROH
ReactionCard
2 Thiol-containing reductant+ROOHOxidized thiol-containing reductant+Thumb+ROH
2 Thiol-containing reductant + ROOH ↔ Oxidized thiol-containing reductant + Water + ROH
ReactionCard
Thumb
an organic hydroperoxide + NADH + H+ → an alcohol + NAD+ + H2O
ReactionCard
Complex Reactions:
2 R'-SH+ROOHR'-S-S-R'+Thumb+ROH
2 R'-SH + ROOH → R'-S-S-R' + Water + ROH
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000142WaterMetaboCard
GO Classification:
Function
antioxidant activity
catalytic activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
peroxiredoxin activity
Process
cell redox homeostasis
cellular homeostasis
cellular process
metabolic process
oxidation reduction
Gene Properties
Locus tag: PA0139
Strand: +
Entrez Gene ID: 879431
Accession: NP_248829.1
GI: 15595337
Sequence start: 158199
Sequence End: 158762
Sequence Length: 563
Gene Sequence:
>PA0139
ATGTCCCTGATCAACACTCAAGTCCAACCGTTCAAGGTCAACGCTTTCCACAACGGCAAGTTCATCGAGGTGACCGAGGAATCCCTGAAGGGCAAGTGGTCGGTCCTGATCTTCATGCCGGCTGCCTTCACCTTCAACTGCCCGACCGAGATCGAAGACGCCGCCAACAACTACGGCGAGTTCCAGAAAGCCGGTGCCGAGGTCTACATCGTGACCACCGACACCCACTTCTCGCACAAGGTCTGGCACGAAACCTCCCCGGCAGTCGGCAAGGCCCAGTTCCCGCTGATCGGCGACCCGACCCACCAGCTGACCAACGCCTTCGGCGTGCACATCCCGGAAGAAGGCCTGGCCCTGCGCGGTACCTTCGTGATCAACCCGGAAGGCGTGATCAAGACCGTCGAGATCCACTCCAACGAGATCGCCCGTGACGTCGGCGAGACCGTGCGCAAGCTGAAGGCCGCCCAGTACACCGCCGCCCACCCGGGCGAAGTCTGCCCGGCCAAGTGGAAGGAAGGCGAGAAGACCCTCGCTCCGTCCCTGGACCTGGTCGGCAAGATCTAA
Protein Properties
Protein Residues: 187
Protein Molecular Weight: 20.5 kDa
Protein Theoretical pI: 6.3
Hydropathicity (GRAVY score): -0.182
Charge at pH 7 (predicted): -3.14
Protein Sequence:
>PA0139
MSLINTQVQPFKVNAFHNGKFIEVTEESLKGKWSVLIFMPAAFTFNCPTEIEDAANNYGEFQKAGAEVYIVTTDTHFSHKVWHETSPAVGKAQFPLIGDPTHQLTNAFGVHIPEEGLALRGTFVINPEGVIKTVEIHSNEIARDVGETVRKLKAAQYTAAHPGEVCPAKWKEGEKTLAPSLDLVGKI
References
External Links:
Resource Link
Genome ID: PA0139
Entrez Gene ID: 879431
NCBI Protein ID: 15595337
General Reference: PaperBLAST - Find papers about PA0139 and its homologs