Identification
Name: DNA gyrase subunit B
Synonyms: Not Available
Gene Name: gyrB
Enzyme Class: Not Available
Biological Properties
General Function: DNA topological change, response to drug, transcription, DNA-templated
Specific Function: ATP binding, DNA binding, DNA topoisomerase type II (ATP-hydrolyzing) activity
Cellular Location: Cytoplasmic
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    a double stranded DNA + ATP = a negatively supercoiled DNA + ADP + phosphate
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    ATP binding
    DNA binding
    DNA topoisomerase type II (ATP-hydrolyzing) activity
    Process
    DNA topological change
    response to drug
    transcription, DNA-templated
    Gene Properties
    Locus tag: PA0004
    Strand: +
    Entrez Gene ID: 879230
    Accession: NP_064724.1
    GI: 15595202
    Sequence start: 4275
    Sequence End: 6695
    Sequence Length: 2420
    Gene Sequence:
    >PA0004
    ATGAGCGAGAACAACACGTACGACTCTTCCAGCATCAAGGTGCTGAAGGGGCTGGATGCCGTACGCAAGCGCCCCGGCATGTACATCGGCGACACCGACGATGGCACCGGTCTGCACCACATGGTGTTCGAGGTGGTGGATAACTCCATCGACGAAGCGCTGGCCGGTTACTGCAGCGAAATCAGCATCACCATCCATACGGATGAGTCGATCACTGTCCGCGACAATGGACGCGGTATTCCGGTGGATATCCACAAGGAAGAAGGGGTTTCTGCGGCGGAAGTGATCATGACCGTCCTCCACGCCGGCGGCAAGTTCGACGACAACACCTACAAGGTGTCCGGCGGCTTGCACGGTGTGGGCGTCTCGGTGGTGAACGCGCTGTCCCATGAACTACGCCTGACCATCCGTCGCCACAACAAGGTCTGGGAACAGGTCTACCACCACGGCGTTCCGCAGTTCCCACTGCGCGAAGTGGGCGAGACCGATGGCTCCGGCACCGAAGTTCACTTCAAGCCGTCCCCGGAGACCTTCAGCAACATCCACTTCAGTTGGGACATCCTGGCCAAGCGCATCCGCGAGCTGTCCTTCCTCAACTCCGGCGTCGGCATCCTGCTGCGCGACGAGCGTACCGGCAAGGAGGAGCTGTTCAAGTACGAAGGCGGTCTGAAGGCCTTCGTCGAGTACCTGAACACCAACAAGACCGCGGTGAACGAGGTATTCCACTTCAACGTCCAGCGTGAAGAGGACGGCGTGGGTGTGGAAGTCGCCTTGCAGTGGAACGACAGCTTCAACGAGAACCTGCTCTGCTTCACCAACAACATCCCGCAGCGTGACGGCGGCACCCACCTGGCCGGTTTCCGTTCGGCGCTGACGCGTAACCTGAACAACTACATCGAGGCCGAAGGCCTGGCGAAGAAGTTCAAGATCGCCACCACCGGCGACGATGCCCGCGAAGGCCTCACCGCGATCATCTCGGTGAAGGTACCGGACCCGAAGTTCAGCTCGCAGACCAAGGACAAGCTGGTCTCCTCCGAGGTGAAGACTGCGGTGGAACAGGAGATGGGCAAGTACTTCGCCGACTTCCTGCTGGAGAATCCCAACGAAGCCAAGGCCGTGGTCGGCAAGATGATCGACGCCGCCCGTGCCCGCGAGGCCGCGCGCAAGGCGCGCGAGATGACCCGCCGCAAGGGCGCGCTGGACATCGCCGGCCTGCCCGGCAAACTGGCCGATTGCCAGGAAAAGGACCCGGCGCTCTCCGAACTGTACATCGTGGAGGGTGACTCCGCGGGCGGTTCCGCCAAGCAGGGCCGCAATCGCCGGACCCAGGCGATCCTGCCGCTCAAGGGCAAGATCCTCAACGTCGAAAAGGCGCGCTTCGACAAGATGCTCTCCTCCCAGGAGGTCGGTACGCTGATCACCGCCCTGGGCTGTGGCATCGGCCGCGAGGAATACAACATCGACAAGCTGCGCTACCACAACATCATCATCATGACCGATGCTGACGTCGACGGTTCGCACATCCGCACCCTGCTGTTGACCTTCTTCTTCCGCCAGATGCCCGAGCTGATCGAGCGTGGCTACATCTACATCGCCCAGCCCCCGTTGTACAAGGTCAAGCGCGGCAAGCAGGAGCAGTACATCAAGGACGACCAGGCCATGGAAGAGTACATGACCCAGTCGGCCCTGGAAGACGCCAGCCTGCACGTCAACGAGCACGCTCCGGGCCTGTCCGGGGCGGCGCTGGAGAAACTGGTCAACGAGTATCGCGGGGTGATCGCCACCCTCAAGCGCCTGTCGCGCCTGTACCCCCAGGAGCTGACCGAGCACTTCATCTACCTGCCTACCGTGTCGGTGGACGACCTGGCTAACGAGTCGGCCATGCAGGGCTGGTTGGAGAAGTTCCAGGCGCGCCTGACCGCCGCCGAGAAGTCCGGCCTGACCTACAAGGCCAGCCTGCGCGAAGACCGCGAGCGCCACCTGTGGCTGCCCGAGGTGGAACTGGTGGCCCACGGCCTGTCCAGCTACGTCACCTTCAACCGTGACTTCTTCGCCAGCAATGACTACCGCTCGGTGTCGCTGCTCGGCGACCAGCTGAACAGCCTGCTGGAAGACGGCGCCTACGTGCAGAAGGGTGAGCGCAAGCGCCCGATCAGCGCCTTCAAGGACGGCCTGGACTGGCTGATGGCCGAAGGTACCAAGCGCCACAGCATCCAGCGATACAAGGGGCTGGGCGAGATGAACCCTGAGCAGCTGTGGGAAACCACCATGGATCCGAACGTCCGGCGCATGCTCAAGGTGACCATCGAGGATGCCATCGCCGCCGACCAGATCTTCAACACCCTGATGGGCGATGCCGTGGAGCCGCGCCGCGACTTCATCGAAAGCAACGCGCTGGCGGTGTCGAACCTGGACGTGTGA
    Protein Properties
    Protein Residues: 806
    Protein Molecular Weight: 90.2 kDa
    Protein Theoretical pI: 5.74
    Hydropathicity (GRAVY score): -0.411
    Charge at pH 7 (predicted): -15.76
    Protein Sequence:
    >PA0004
    MSENNTYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNSIDEALAGYCSEISITIHTDESITVRDNGRGIPVDIHKEEGVSAAEVIMTVLHAGGKFDDNTYKVSGGLHGVGVSVVNALSHELRLTIRRHNKVWEQVYHHGVPQFPLREVGETDGSGTEVHFKPSPETFSNIHFSWDILAKRIRELSFLNSGVGILLRDERTGKEELFKYEGGLKAFVEYLNTNKTAVNEVFHFNVQREEDGVGVEVALQWNDSFNENLLCFTNNIPQRDGGTHLAGFRSALTRNLNNYIEAEGLAKKFKIATTGDDAREGLTAIISVKVPDPKFSSQTKDKLVSSEVKTAVEQEMGKYFADFLLENPNEAKAVVGKMIDAARAREAARKAREMTRRKGALDIAGLPGKLADCQEKDPALSELYIVEGDSAGGSAKQGRNRRTQAILPLKGKILNVEKARFDKMLSSQEVGTLITALGCGIGREEYNIDKLRYHNIIIMTDADVDGSHIRTLLLTFFFRQMPELIERGYIYIAQPPLYKVKRGKQEQYIKDDQAMEEYMTQSALEDASLHVNEHAPGLSGAALEKLVNEYRGVIATLKRLSRLYPQELTEHFIYLPTVSVDDLANESAMQGWLEKFQARLTAAEKSGLTYKASLREDRERHLWLPEVELVAHGLSSYVTFNRDFFASNDYRSVSLLGDQLNSLLEDGAYVQKGERKRPISAFKDGLDWLMAEGTKRHSIQRYKGLGEMNPEQLWETTMDPNVRRMLKVTIEDAIAADQIFNTLMGDAVEPRRDFIESNALAVSNLDV
    References
    External Links:
    Resource Link
    Genome ID: PA0004
    Entrez Gene ID: 879230
    NCBI Protein ID: 15595202
    General Reference: PaperBLAST - Find papers about PA0004 and its homologs