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Record Information |
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| Version |
1.0 |
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| Update Date |
1/22/2018 12:54:54 PM |
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Metabolite ID | PAMDB110630 |
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Identification |
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| Name: |
N-formimino-L-glutamate |
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| Description: | Conjugate base of N-formimidoyl-L-glutamic acid having both carboxy groups in anionic form and the imine nitrogen protonated. |
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Structure |
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| Synonyms: | -
N-formimino-glutamate
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formiminoglutamate
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formimino-glu
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α-formamidinoglutarate
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N-formimidoyl-L-glutamate
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Chemical Formula: |
C6H9N2O4
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| Average Molecular Weight: |
173.15 |
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| Monoisotopic Molecular
Weight: |
175.0718818519 |
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| InChI Key: |
NRXIKWMTVXPVEF-BYPYZUCNSA-M |
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| InChI: |
InChI=1S/C6H10N2O4/c7-3-8-4(6(11)12)1-2-5(9)10/h3-4H,1-2H2,(H2,7,8)(H,9,10)(H,11,12)/p-1/t4-/m0/s1 |
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| CAS
number: |
816-90-0 |
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| IUPAC Name: | (2S)-2-[(iminiumylmethyl)amino]pentanedioate |
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Traditional IUPAC Name: |
N-formimino-L-glutamate |
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| SMILES: | [CH](=[N+])NC(C([O-])=O)CCC([O-])=O |
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Chemical Taxonomy |
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Taxonomy Description | This compound belongs to the class of chemical entities known as glutamic acid and derivatives. These are compounds containing glutamic acid or a derivative thereof resulting from reaction of glutamic acid at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. |
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Kingdom |
Chemical entities |
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| Super Class | Organic compounds |
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Class |
Organic acids and derivatives |
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| Sub Class | Carboxylic acids and derivatives |
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Direct Parent |
Glutamic acid and derivatives |
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| Alternative Parents |
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| Substituents |
- Glutamic acid or derivatives
- Dicarboxylic acid or derivatives
- Fatty acid
- Amidine
- Carboxylic acid amidine
- Carboxylic acid
- Carboximidamide
- Propargyl-type 1,3-dipolar organic compound
- Organic 1,3-dipolar compound
- Formamidine
- Organooxygen compound
- Carbonyl group
- Organic nitrogen compound
- Organonitrogen compound
- Hydrocarbon derivative
- Organic oxygen compound
- Organic oxide
- Organopnictogen compound
- Aliphatic acyclic compound
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| Molecular Framework |
Aliphatic acyclic compounds |
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| External Descriptors |
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Physical Properties |
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| State: |
Solid |
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| Charge: | -1 |
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Melting point: |
Not Available |
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| Experimental Properties: |
| Property | Value | Reference |
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| Melting Point | Not Available | Not Available | | Boiling Point | Not Available | Not Available | | Water Solubility | Not Available | Not Available | | LogP | Not Available | Not Available |
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| Predicted Properties |
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Biological Properties |
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| Cellular Locations: |
Not Available |
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| Reactions: | |
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Pathways: |
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Spectra |
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| Spectra: |
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References |
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| References: |
- Hilton JF, Christensen KE, Watkins D, Raby BA, Renaud Y, de la Luna S, Estivill X, MacKenzie RE, Hudson TJ, Rosenblatt DS: The molecular basis of glutamate formiminotransferase deficiency. Hum Mutat. 2003 Jul;22(1):67-73. [12815595 ]
- Haurani FI, Hall CA, Rubin R: Megaloblastic anemia as a result of an abnormal transcobalamin II (Cardeza). J Clin Invest. 1979 Nov;64(5):1253-9. [500809 ]
- Perry TL, Applegarth DA, Evans ME, Hansen S, Jellum E: Metabolic studies of a family with massive formiminoglutamic aciduria. Pediatr Res. 1975 Mar;9(3):117-22. [235753 ]
- Verhoeven NM, Wanders RJ, Poll-The BT, Saudubray JM, Jakobs C: The metabolism of phytanic acid and pristanic acid in man: a review. J Inherit Metab Dis. 1998 Oct;21(7):697-728. [9819701 ]
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| Synthesis Reference: |
Tabor, Herbert; Rabinowitz, Jesse C. Insts. Formiminoglycine, formimino-L-aspartic acid, and formimino-L-glutamic acid. |
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| Material Safety Data Sheet (MSDS) |
Not Available |
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Links |
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| External Links: |
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