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Record Information |
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| Version |
1.0 |
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| Update Date |
1/22/2018 12:54:54 PM |
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Metabolite ID | PAMDB110466 |
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Identification |
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| Name: |
acetamide |
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| Description: | Acetamide is found in red beetroot. Acetamide (or acetic acid amide or ethanamide), CH3CONH2, the amide of acetic acid, is a white crystalline solid in pure form. It is produced by dehydrating ammonium acetate:Acetamide has been shown to exhibit anti-microbial, anti-inflammatory, anti-arthritic and antibiotic functions (PMID 9550095 , 20452462 , 20452462 , 14965292 ).Acetamide belongs to the family of Primary Carboxylic Acid Amides. These are compounds comprising primary carboxylic acid amide functional group, with the general structure RC(=O)NH2. |
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Structure |
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| Synonyms: | - Acetamid
- Acetic acid amide
- Azetamid
- CH3CONH2
- Essigsaeureamid
- Ethanamid
- Ethanamide
- Methanecarboxamide
- Acetate amide
- Acetimidic acid
- ACM
- Amid kyseliny octove
- Acetamide, monosodium salt
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Chemical Formula: |
C2H5NO
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| Average Molecular Weight: |
59.068 |
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| Monoisotopic Molecular
Weight: |
59.0371137878 |
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| InChI Key: |
DLFVBJFMPXGRIB-UHFFFAOYSA-N |
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| InChI: |
InChI=1S/C2H5NO/c1-2(3)4/h1H3,(H2,3,4) |
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| CAS
number: |
60-35-5 |
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| IUPAC Name: | acetamide |
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Traditional IUPAC Name: |
acetamide |
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| SMILES: | CC(=O)N |
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Chemical Taxonomy |
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Taxonomy Description | This compound belongs to the class of chemical entities known as carboximidic acids. These are organic acids with the general formula RC(=N)-OH (R=H, organic group). |
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Kingdom |
Chemical entities |
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| Super Class | Organic compounds |
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Class |
Organic acids and derivatives |
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| Sub Class | Carboximidic acids and derivatives |
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Direct Parent |
Carboximidic acids |
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| Alternative Parents |
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| Substituents |
- Carboximidic acid
- Organic nitrogen compound
- Organic oxygen compound
- Organopnictogen compound
- Hydrocarbon derivative
- Organooxygen compound
- Organonitrogen compound
- Aliphatic acyclic compound
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| Molecular Framework |
Aliphatic acyclic compounds |
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| External Descriptors |
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Physical Properties |
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| State: |
Not Available |
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| Charge: | 0 |
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Melting point: |
82 - 83 °C |
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| Experimental Properties: |
| Property | Value | Reference |
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| Melting Point | 82 - 83 °C | Not Available | | Boiling Point | Not Available | Not Available | | Water Solubility | 2250 mg/mL at 25 °C | Not Available | | LogP | -1.26 | Not Available |
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| Predicted Properties |
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Biological Properties |
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| Cellular Locations: |
Not Available |
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| Reactions: | |
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Pathways: |
Not Available |
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Spectra |
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| Spectra: |
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References |
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| References: |
- Yalcin I, Kaymakcioglu BK, Oren I, Sener E, Temiz O, Akin A, Altanlar N: Synthesis and microbiological activity of some novel N-(2-hydroxyl-5-substitutedphenyl)benzacetamides, phenoxyacetamides and thiophenoxyacetamides as the possible metabolites of antimicrobial active benzoxazoles. Farmaco. 1997 Nov;52(11):685-9. [9550095 ]
- Jawed H, Shah SU, Jamall S, Simjee SU: N-(2-hydroxy phenyl) acetamide inhibits inflammation-related cytokines and ROS in adjuvant-induced arthritic (AIA) rats. Int Immunopharmacol. 2010 Aug;10(8):900-5. doi: 10.1016/j.intimp.2010.04.028. Epub 2010 May 7. [20452462 ]
- Muri EM, Williamson JS: Anti-Helicobacter pylori agents. An update. Mini Rev Med Chem. 2004 Feb;4(2):201-6. [14965292 ]
- Yannai, Shmuel. (2004) Dictionary of food compounds with CD-ROM: Additives, flavors, and ingredients. Boca Raton: Chapman & Hall/CRC.
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| Synthesis Reference: |
Not Available |
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| Material Safety Data Sheet (MSDS) |
Download (PDF) |
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Links |
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| External Links: |
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