glucosyl-(heptosyl)2-Kdo2-lipid A (PAMDB006337)
| Record Information | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Version | 1.0 | |||||||||
| Update Date | 1/22/2018 12:54:54 PM | |||||||||
| Metabolite ID | PAMDB006337 | |||||||||
| Identification | ||||||||||
| Name: | glucosyl-(heptosyl)2-Kdo2-lipid A | |||||||||
| Description: | Glucosyl-(heptosyl)2-Kdo2-lipid A is an intermediate in lipid A-core biosynthesis pathway in E.coli. It is a substrate for the enzyme lipopolysaccharide core heptose (I) kinase which catalyzes the reaction glucosyl-(heptosyl)2-Kdo2-lipid A + ATP -> glucosyl-(heptosyl)2-Kdo2-lipid A-phosphate + ADP + H+. It is also a product for enzyme lipopolysaccharide glucosyltransferase I which catalyzes reaction UDP-alpha-D-glucose + (heptosyl)2-Kdo2-lipid A -> glucosyl-(heptosyl)2-Kdo2-lipid A + UDP + H+ (BioCyc compound: CPD0-932). | |||||||||
| Structure |
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| Synonyms: | Not Available | |||||||||
| Chemical Formula: | C130H230N2O56P2 | |||||||||
| Average Molecular Weight: | 2779.179 | |||||||||
| Monoisotopic Molecular Weight: | 2777.471939609 | |||||||||
| InChI Key: | UMRPQNDYTAXFNB-AXIBLZMKSA-H | |||||||||
| InChI: | InChI=1S/C130H236N2O56P2/c1-7-13-19-25-31-37-38-44-50-56-62-68-98(148)173-85(66-60-54-48-42-35-29-23-17-11-5)72-100(150)178-119-102(132-96(146)71-84(65-59-53-47-41-34-28-22-16-10-4)172-97(147)67-61-55-49-43-36-30-24-18-12-6)122(170-80-93-105(153)118(177-99(149)70-83(139)64-58-52-46-40-33-27-21-15-9-3)101(123(175-93)188-190(167,168)169)131-95(145)69-82(138)63-57-51-45-39-32-26-20-14-8-2)176-94(117(119)187-189(164,165)166)81-171-129(127(160)161)74-91(184-130(128(162)163)73-86(140)103(151)114(185-130)89(143)77-135)116(115(186-129)90(144)78-136)181-125-110(158)121(109(157)112(179-125)87(141)75-133)183-126-111(159)120(108(156)113(180-126)88(142)76-134)182-124-107(155)106(154)104(152)92(79-137)174-124/h82-94,101-126,133-144,151-159H,7-81H2,1-6H3,(H,131,145)(H,132,146)(H,160,161)(H,162,163)(H2,164,165,166)(H2,167,168,169)/p-6/t82-,83-,84-,85-,86-,87+,88+,89-,90-,91-,92-,93-,94-,101-,102-,103-,104-,105-,106+,107-,108-,109-,110+,111+,112-,113-,114-,115-,116-,117-,118-,119-,120+,121+,122-,123-,124?,125-,126-,129-,130-/m1/s1 | |||||||||
| CAS number: | Not Available | |||||||||
| IUPAC Name: | Not Available | |||||||||
| Traditional IUPAC Name: | Not Available | |||||||||
| SMILES: | [H][C@@]1(O[C@@](C[C@@H](O)[C@H]1O)(O[C@@H]1C[C@@](OC[C@H]2O[C@@H](OC[C@H]3O[C@H](OP([O-])([O-])=O)[C@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H]3O)[C@H](NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@H]2OP([O-])([O-])=O)(O[C@]([H])([C@H](O)CO)[C@@H]1O[C@H]1O[C@H]([C@@H](O)CO)[C@@H](O)[C@H](O[C@H]2O[C@H]([C@@H](O)CO)[C@@H](O)[C@H](OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]2O)[C@@H]1O)C([O-])=O)C([O-])=O)[C@H](O)CO | |||||||||
| Chemical Taxonomy | ||||||||||
| Taxonomy Description | Not Available | |||||||||
| Kingdom | Not Available | |||||||||
| Super Class | Not Available | |||||||||
| Class | Not Available | |||||||||
| Sub Class | Not Available | |||||||||
| Direct Parent | Not Available | |||||||||
| Alternative Parents | Not Available | |||||||||
| Substituents | Not Available | |||||||||
| Molecular Framework | Not Available | |||||||||
| External Descriptors | Not Available | |||||||||
| Physical Properties | ||||||||||
| State: | Not Available | |||||||||
| Charge: | Not Available | |||||||||
| Melting point: | Not Available | |||||||||
| Experimental Properties: |
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| Biological Properties | ||||||||||
| Cellular Locations: | Cytoplasm | |||||||||
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| Biological Properties | ||||||||||
| Cellular Locations: | Cytoplasm | |||||||||
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| Spectra | ||||||||||
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| References | ||||||||||
| References: | Not Available | |||||||||
| Synthesis Reference: | Not Available | |||||||||
| Material Safety Data Sheet (MSDS) | Not Available | |||||||||
| Links | ||||||||||
| External Links: |
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Enzymes
- General function:
- Involved in biosynthetic process
- Specific function:
- Involved in the addition of the first glucose residue to the lipopolysaccharide core
- Gene Name:
- rfaG
- Locus Tag:
- PA5010
- Molecular weight:
- 42.2 kDa
- General function:
- Involved in transferase activity, transferring phosphorus-containing groups
- Specific function:
- Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core
- Gene Name:
- rfaP
- Locus Tag:
- PA5009
- Molecular weight:
- 31.3 kDa