N-carbamoyl-L-aspartate (PAMDB006306)

IdentificationTaxonomyPhysical PropertiesBiological PropertiesSpectraConcentrationsLinksReferencesEnzymes Transporters
Proteins (3280)
Record Information
Version 1.0
Update Date 1/22/2018 12:54:54 PM
Metabolite IDPAMDB006306
Identification
Name: N-carbamoyl-L-aspartate
Description:N-carbamoyl-L-aspartate, also known as ureidosuccinic acid, is an intermediary product in pyrimidine metabolism. It is generated by the action of dihydroorotase which catalyzes the following reaction: 4,5-Dihydroorotic acid + Water <=> Ureidosuccinic acid + H+
Structure
Thumb
Synonyms:
  • N-Carbamoyl-L-aspartic acid
Chemical Formula: C5H6N2O5
Average Molecular Weight: 174.113
Monoisotopic Molecular Weight: 174.028768461
InChI Key: HLKXYZVTANABHZ-UHFFFAOYSA-L
InChI:InChI=1S/C5H8N2O5/c6-5(12)7-2(4(10)11)1-3(8)9/h2H,1H2,(H,8,9)(H,10,11)(H3,6,7,12)/p-2
CAS number: Not Available
IUPAC Name:Not Available
Traditional IUPAC Name: Not Available
SMILES:OC(=N)NC(CC([O-])=O)C([O-])=O
Chemical Taxonomy
Taxonomy DescriptionNot Available
Kingdom Not Available
Super ClassNot Available
Class Not Available
Sub ClassNot Available
Direct Parent Not Available
Alternative Parents Not Available
Substituents Not Available
Molecular Framework Not Available
External Descriptors Not Available
Physical Properties
State: Not Available
Charge:Not Available
Melting point: Not Available
Experimental Properties:
PropertyValueSource
Predicted Properties
Biological Properties
Cellular Locations:Cytoplasm
Reactions:
L-Aspartic acid + L-Aspartic acid > N-carbamoyl-L-aspartate
Carbamoylphosphate + L-Aspartic acid + L-Aspartic acid > Phosphate + Hydrogen ion + N-carbamoyl-L-aspartate
N-carbamoyl-L-aspartate + Hydrogen ion > Water + 4,5-Dihydroorotic acid + 4,5-Dihydroorotic acid
SMPDB Pathways:
Aspartate metabolismPW000787 Pw000787Pw000787 greyscalePw000787 simple
Pyrimidine metabolismPW000942 Pw000942Pw000942 greyscalePw000942 simple
Biological Properties
Cellular Locations: Cytoplasm
Reactions:
L-Aspartic acid + L-Aspartic acid > N-carbamoyl-L-aspartate
Carbamoylphosphate + L-Aspartic acid + L-Aspartic acid > Phosphate + Hydrogen ion + N-carbamoyl-L-aspartate
N-carbamoyl-L-aspartate + Hydrogen ion > Water + 4,5-Dihydroorotic acid + 4,5-Dihydroorotic acid
Pathways:
Spectra
Spectra:
References
References: Not Available
Synthesis Reference: Not Available
Material Safety Data Sheet (MSDS) Not Available
External Links:
ResourceLink

Enzymes

Protein Details
• Dihydroorotase
General function:
Involved in hydrolase activity
Specific function:
(S)-dihydroorotate + H(2)O = N-carbamoyl-L- aspartate
Gene Name:
pyrC
Locus Tag:
PA3527
Molecular weight:
38.4 kDa
Reactions
(S)-dihydroorotate + H(2)O = N-carbamoyl-L-aspartate.
Protein Details
• Aspartate carbamoyltransferase catalytic chain
General function:
Involved in carboxyl- or carbamoyltransferase activity
Specific function:
Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate
Gene Name:
pyrB
Locus Tag:
PA0402
Molecular weight:
36.6 kDa
Reactions
Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate.