(S)-2,3,4,5-tetrahydrodipicolinate (PAMDB006304)

IdentificationTaxonomyPhysical PropertiesBiological PropertiesSpectraConcentrationsLinksReferencesEnzymes Transporters
Proteins (3280)
Record Information
Version 1.0
Update Date 1/22/2018 11:54:54 AM
Metabolite IDPAMDB006304
Identification
Name: (S)-2,3,4,5-tetrahydrodipicolinate
Description:(S)-2,3,4,5-tetrahydrodipicolinate is an intermediate in L-lysine biosynthesis I pathway in E.coli. It is a substrate for the enzyme tetrahydrodipicolinate succinylase which catalyzes the reaction (S)-2,3,4,5-tetrahydrodipicolinate + succinyl-CoA + H2O -> N-succinyl-2-amino-6-ketopimelate + coenzyme A. It is also a product for enzyme 4-hydroxy-tetrahydrodipicolinate reductase which catalyzes reaction (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH + H+ -> (S)-2,3,4,5-tetrahydrodipicolinate + NADP+ + H2O (BioCyc compound: DELTA1-PIPERIDEINE-2-6-DICARBOXYLATE).
Structure
Thumb
Synonyms:
  • (S)-2,3,4,5-Tetrahydrodipicolinic acid
Chemical Formula: C7H7NO4
Average Molecular Weight: 169.137
Monoisotopic Molecular Weight: 169.038604869
InChI Key: CXMBCXQHOXUCEO-UHFFFAOYSA-L
InChI:InChI=1S/C7H9NO4/c9-6(10)4-2-1-3-5(8-4)7(11)12/h4H,1-3H2,(H,9,10)(H,11,12)/p-2
CAS number: Not Available
IUPAC Name:Not Available
Traditional IUPAC Name: Not Available
SMILES:[O-]C(=O)C1CCCC(=N1)C([O-])=O
Chemical Taxonomy
Taxonomy DescriptionNot Available
Kingdom Not Available
Super ClassNot Available
Class Not Available
Sub ClassNot Available
Direct Parent Not Available
Alternative Parents Not Available
Substituents Not Available
Molecular Framework Not Available
External Descriptors Not Available
Physical Properties
State: Not Available
Charge:Not Available
Melting point: Not Available
Experimental Properties:
PropertyValueSource
Predicted Properties
Biological Properties
Cellular Locations:Cytoplasm
Reactions:
(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + Hydrogen ion + NADPH + (2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH > Water + NADP + (S)-2,3,4,5-tetrahydrodipicolinate
(S)-2,3,4,5-tetrahydrodipicolinate + Succinyl-CoA + Water + Succinyl-CoA > Coenzyme A + N-Succinyl-2-amino-6-ketopimelate
SMPDB Pathways:
Lysine biosynthesisPW000771 Pw000771Pw000771 greyscalePw000771 simple
Biological Properties
Cellular Locations: Cytoplasm
Reactions:
(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + Hydrogen ion + NADPH + (2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH > Water + NADP + (S)-2,3,4,5-tetrahydrodipicolinate
(S)-2,3,4,5-tetrahydrodipicolinate + Succinyl-CoA + Water + Succinyl-CoA > Coenzyme A + N-Succinyl-2-amino-6-ketopimelate
Pathways:
Spectra
Spectra:
Spectrum TypeDescriptionSplash Key
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-00di-0900000000-3bbcafe91a30720bb736View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-00di-0900000000-1347c32500acf52bc79dView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0006-9100000000-c32da1dc7cc3fafb5fc0View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-014i-0900000000-643f36ee3510b74a2eb3View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-014i-1900000000-d8305875fe20207dff59View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-001l-9300000000-36365a0fe19d6e926f92View in MoNA
References
References: Not Available
Synthesis Reference: Not Available
Material Safety Data Sheet (MSDS) Not Available
External Links:
ResourceLink