P. aeruginosa Metabolome Database: L-Glutamyl-tRNA(Glu) (PAMDB004290)

Identification Taxonomy Physical Properties Biological Properties Spectra Concentrations Links References Enzymes Transporters

Proteins (3280)

Record Information

Version

1.0

Update Date

1/22/2018 11:54:54 AM

Metabolite ID

PAMDB004290

Identification

Name:

L-Glutamyl-tRNA(Glu)

Description:

This list contains a list of EC numbers for the fourth group, EC 4, lyases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.

Structure

🔍MOL SDF PDB SMILES InChI View Structure

Synonyms:

(2S,4R)-2-amino-4-Hydroxypentanedioate
(2S,4R)-2-amino-4-Hydroxypentanedioic acid
L-erythro-4-Hydroxyglutamate
L-erythro-4-Hydroxyglutamic acid

Chemical Formula:

C₅H₉NO₅

Average Molecular Weight:

163.1287

Monoisotopic Molecular Weight:

163.048072403

InChI Key:

HBDWQSHEVMSFGY-STHAYSLISA-N

InChI:

InChI=1S/C5H9NO5/c6-2(4(8)9)1-3(7)5(10)11/h2-3,7H,1,6H2,(H,8,9)(H,10,11)/t2-,3+/m0/s1

CAS number:

Not Available

IUPAC Name:

(2S,4R)-2-amino-4-hydroxypentanedioic acid

Traditional IUPAC Name:

(2S,4R)-2-amino-4-hydroxypentanedioic acid

SMILES:

N[C@@H](C[C@@H](O)C(O)=O)C(O)=O

Chemical Taxonomy

Taxonomy Description

This compound belongs to the class of organic compounds known as hydroxy fatty acids. These are fatty acids in which the chain bears a hydroxyl group.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Fatty Acyls

Sub Class

Fatty acids and conjugates

Direct Parent

Hydroxy fatty acids

Alternative Parents

Substituents

Hydroxy fatty acid
L-alpha-amino acid
Alpha-amino acid or derivatives
Alpha-amino acid
Short-chain hydroxy acid
Amino fatty acid
Hydroxy acid
Dicarboxylic acid or derivatives
Alpha-hydroxy acid
1,3-aminoalcohol
Secondary alcohol
Carboxylic acid
Carboxylic acid derivative
Hydrocarbon derivative
Primary amine
Organooxygen compound
Organonitrogen compound
Primary aliphatic amine
Carbonyl group
Amine
Alcohol
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

glutamic acid derivative (CHEBI:21285 )

Physical Properties

State:

Not Available

Charge:

-1

Melting point:

Not Available

Experimental Properties:

Property	Value	Source

Predicted Properties

Property	Value	Source
Water Solubility	74.3 mg/mL	ALOGPS
logP	-3.7	ALOGPS
logP	-4.2	ChemAxon
logS	-0.34	ALOGPS
pKa (Strongest Acidic)	1.68	ChemAxon
pKa (Strongest Basic)	9.16	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	6	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	120.85 Å²	ChemAxon
Rotatable Bond Count	4	ChemAxon
Refractivity	32.74 m³·mol^-1	ChemAxon
Polarizability	14.08 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	1	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	Yes	ChemAxon
MDDR-like Rule	Yes	ChemAxon

Biological Properties

Cellular Locations:

Cytoplasm

Reactions:

L-Glutamyl-tRNA(Glu) + NADPH + Hydrogen ion + tRNA(Glu) <> (S)-4-Amino-5-oxopentanoate + tRNA(Glu) + NADP + L-Glutamyl-tRNA(Glu)
tRNA(Glu) + L-Glutamate + Adenosine triphosphate + tRNA(Glu) <> L-Glutamyl-tRNA(Glu) + Pyrophosphate + Adenosine monophosphate + L-Glutamyl-tRNA(Glu)

Pathways:

Aminoacyl-tRNA biosynthesis pae00970
Metabolic pathways pae01100
Porphyrin and chlorophyll metabolism pae00860

Spectra

Spectra:

Spectrum Type	Description	Splash Key
GC-MS	GC-MS Spectrum - GC-MS	Not Available
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-0fr2-1900000000-1952d82430e8d4d017ec	View in MoNA
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-0g4i-8900000000-9b552b5028c7cac0636c	View in MoNA
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-006x-9200000000-69e6a42e7b8c893be2b0	View in MoNA
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-03di-3900000000-a1ac74b59a8487175409	View in MoNA
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-00di-9600000000-b341efd7d7ac7e6a7652	View in MoNA
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-00di-9100000000-a0987d89d6b50b5ee46a	View in MoNA

References

References:

Not Available

Synthesis Reference:

Not Available

Material Safety Data Sheet (MSDS)

Not Available

Links

External Links:

Resource	Link
CHEBI ID	21285
HMDB ID	Not Available
Pubchem Compound ID	440854
Kegg ID	C02987
ChemSpider ID	389696
Wikipedia ID	Not Available
BioCyc ID	Not Available

L-Glutamyl-tRNA(Glu) (PAMDB004290)

Structure for L-Glutamyl-tRNA(Glu) (PAMDB004290)