|
Record Information |
|---|
| Version |
1.0 |
|---|
| Update Date |
1/22/2018 11:54:54 AM |
|---|
|
Metabolite ID | PAMDB003431 |
|---|
|
Identification |
|---|
| Name: |
5'-Phospho-ribosylglycinamide |
|---|
| Description: | 5-Phospho-ribosylglycinamide is an intermediate in puriine biosynthesis. It is a substrate for the enzyme Phosphoribosylglycinamide synthetase (EC:6.3.4.13) (GARS) which catalyses the second step in the de novo biosynthesis of purine. The reaction catalysed by phosphoribosylglycinamide synthetase is the ATP-dependent addition of 5-phosphoribosylamine to glycine to form 5'-phosphoribosylglycinamide. |
|---|
|
Structure |
|
|---|
| Synonyms: | - (2R,3S,4R)-5-(2-aminoacetyl)amino-3,4-dihydroxyoxolan-2-ylmethyl dihydrogen phosphate
- (2R,3S,4R)-5-(2-Aminoacetyl)amino-3,4-dihydroxyoxolan-2-ylmethyl dihydrogen phosphoric acid
- 5'-Phosphoribosylglycinamide
- 5'-Phosphoribosylglycineamide
- GAR
- Glycinamide ribonucleotide
- Glycineamide ribonucleotide
- Glycineamideribotide
- N-glycyl-5-O-phosphono-D-ribofuranosylamine
- N1-(5-Phospho-D-ribosyl)glycinamide
|
|---|
|
Chemical Formula: |
C7H15N2O8P |
|---|
| Average Molecular Weight: |
286.1764 |
|---|
| Monoisotopic Molecular
Weight: |
286.056601978 |
|---|
| InChI Key: |
OBQMLSFOUZUIOB-HJZCUYRDSA-N |
|---|
| InChI: | InChI=1S/C7H15N2O8P/c8-1-4(10)9-7-6(12)5(11)3(17-7)2-16-18(13,14)15/h3,5-7,11-12H,1-2,8H2,(H,9,10)(H2,13,14,15)/t3-,5-,6-,7?/m1/s1 |
|---|
| CAS
number: |
Not Available |
|---|
| IUPAC Name: | {[(2R,3S,4R)-5-(2-aminoacetamido)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid |
|---|
|
Traditional IUPAC Name: |
5'-phosphoribosylglycinamide |
|---|
| SMILES: | NCC(=O)NC1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O |
|---|
|
Chemical Taxonomy |
|---|
|
Taxonomy Description | This compound belongs to the class of organic compounds known as glycosylamines. These are compounds consisting of an?amine?with a?beta-N-glycosidic bond?to a carbohydrate, thus forming a cyclic?hemiaminal ether?bond (alpha-amino ether). |
|---|
|
Kingdom |
Organic compounds |
|---|
| Super Class | Organooxygen compounds |
|---|
|
Class |
Carbohydrates and carbohydrate conjugates |
|---|
| Sub Class | Glycosyl compounds |
|---|
|
Direct Parent |
Glycosylamines |
|---|
| Alternative Parents |
|
|---|
| Substituents |
- N-glycosyl compound
- Monosaccharide phosphate
- Monoalkyl phosphate
- Alkyl phosphate
- Phosphoric acid ester
- Organic phosphoric acid derivative
- Organic phosphate
- Monosaccharide
- Oxolane
- Secondary alcohol
- 1,2-diol
- Oxacycle
- Organoheterocyclic compound
- Organic 1,3-dipolar compound
- Propargyl-type 1,3-dipolar organic compound
- Carboximidic acid derivative
- Carboximidic acid
- Hydrocarbon derivative
- Primary amine
- Organonitrogen compound
- Primary aliphatic amine
- Amine
- Alcohol
- Aliphatic heteromonocyclic compound
|
|---|
| Molecular Framework |
Aliphatic heteromonocyclic compounds |
|---|
| External Descriptors |
|
|---|
|
Physical Properties |
|---|
| State: |
Not Available |
|---|
| Charge: | -1 |
|---|
|
Melting point: |
Not Available |
|---|
| Experimental Properties: |
|
|---|
| Predicted Properties |
|
|---|
|
Biological Properties |
|---|
| Cellular Locations: |
Cytoplasm |
|---|
| Reactions: | |
|---|
|
Pathways: |
Not Available |
|---|
|
Spectra |
|---|
| Spectra: |
|
|---|
|
References |
|---|
| References: |
Not Available |
|---|
| Synthesis Reference: |
Not Available |
|---|
| Material Safety Data Sheet (MSDS) |
Not Available |
|---|
|
Links |
|---|
| External Links: |
| Resource | Link |
|---|
| CHEBI ID | 18349 | | HMDB ID | Not Available | | Pubchem Compound ID | 5459918 | | Kegg ID | Not Available | | ChemSpider ID | 4573646 | | Wikipedia ID | Not Available | | BioCyc ID | Not Available |
|
|---|
