Record Information
Version 1.0
Update Date 1/22/2018 12:54:54 PM
Metabolite IDPAMDB001786
Identification
Name: Nickel
Description:Nickel is a solid, silver-white, hard, malleable transition metal with an atomic number of 28. It resists corrosion even at high temperatures. It is present in many alloys in widespread use, including stainless steels. It may also be present as an impurity in any alloy. Nickel is used in the production of coins, jewellery, and nickel-cadmium batteries, and as a catalyst for the hydrogenation of liquid oils to solid fats such as oleomargarine and vegetable shortening. Nickel-containing dental alloys continue to be used successfully in the provision of various forms of dental care. Many of these alloys have applications in the construction of restorations designed to remain in clinical service for many years, including crowns, fixed bridgework, and removable partial dentures. Furthermore, nickel containing alloys find extensive application in orthodontics, including metallic brackets, arch wires, bands, springs and ligature wires. Many instruments and devises, for example, endodontic instruments also contain nickel.
Structure
Thumb
Synonyms:
  • Carbonyl nickel powder
  • Malleable nickel
  • NI
  • Ni(2+)
  • Ni(II)
  • Ni++
  • Ni2+
  • Nichel
  • NICKEL (II) ION
  • Nickel 200
  • Nickel 201
  • Nickel 204
  • Nickel 205
  • Nickel 211
  • Nickel 212
  • Nickel 213
  • Nickel 222
  • Nickel 223
  • Nickel 229
  • Nickel 270
  • Nickel particles
  • Nickel sponge
  • Nickel(2+)
  • Nickel, ion (Ni2+)
  • Nickelous ion
  • Raney alloy
  • Raney nickel
Chemical Formula: Ni
Average Molecular Weight: 58.6934
Monoisotopic Molecular Weight: 57.935347922
InChI Key: VEQPNABPJHWNSG-UHFFFAOYSA-N
InChI:InChI=1S/Ni/q+2
CAS number: 7440-02-0
IUPAC Name:nickel(2+) ion
Traditional IUPAC Name: nickel(2+) ion
SMILES:[Ni++]
Chemical Taxonomy
Taxonomy DescriptionThis compound belongs to the class of inorganic compounds known as homogeneous transition metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a transition metal atom.
Kingdom Inorganic compounds
Super ClassHomogeneous metal compounds
Class Homogeneous transition metal compounds
Sub ClassNot Available
Direct Parent Homogeneous transition metal compounds
Alternative Parents
Substituents
  • Homogeneous transition metal
  • Inorganic nickel compound
  • Acyclic compound
Molecular Framework Acyclic compounds
External Descriptors
Physical Properties
State: Solid
Charge:2
Melting point: 1455 °C
Experimental Properties:
PropertyValueSource
Predicted Properties
PropertyValueSource
logP0.16ChemAxon
Physiological Charge2ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Biological Properties
Cellular Locations: Cytoplasm
Reactions:
Pathways: Not Available
Spectra
Spectra:
Spectrum TypeDescriptionSplash Key
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-0a4i-9000000000-08256b3c9e2cc1750f60View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-0a4i-9000000000-08256b3c9e2cc1750f60View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0a4i-9000000000-08256b3c9e2cc1750f60View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-0a4i-9000000000-4648ffc6f53552c41503View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-0a4i-9000000000-4648ffc6f53552c41503View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-0a4i-9000000000-4648ffc6f53552c41503View in MoNA
References
References:
  • Biego GH, Joyeux M, Hartemann P, Debry G: Daily intake of essential minerals and metallic micropollutants from foods in France. Sci Total Environ. 1998 Jun 30;217(1-2):27-36. Pubmed: 9695171
  • Hostynek JJ: Sensitization to nickel: etiology, epidemiology, immune reactions, prevention, and therapy. Rev Environ Health. 2006 Oct-Dec;21(4):253-80. Pubmed: 17243350
  • Nielsen FH: How should dietary guidance be given for mineral elements with beneficial actions or suspected of being essential? J Nutr. 1996 Sep;126(9 Suppl):2377S-2385S. Pubmed: 8811801
  • Setcos JC, Babaei-Mahani A, Silvio LD, Mjor IA, Wilson NH: The safety of nickel containing dental alloys. Dent Mater. 2006 Dec;22(12):1163-8. Epub 2006 Jan 6. Pubmed: 16405986
  • Uthus EO, Seaborn CD: Deliberations and evaluations of the approaches, endpoints and paradigms for dietary recommendations of the other trace elements. J Nutr. 1996 Sep;126(9 Suppl):2452S-2459S. Pubmed: 8811811
Synthesis Reference: Lightner, David A.; Crist, B. Vincent; Kalyanam, Nagabushanam; May, Leslie M.; Jackman, Dennis E. The octant rule. 15. Antioctant effects: synthesis and circular dichroism of 2-exo- and 2-endo-alkylbicyclo[2.2.1]heptan-7-ones and bicyclo[3.2.1]octan-8-one
Material Safety Data Sheet (MSDS) Not Available
External Links:
ResourceLink
CHEBI ID28112
HMDB IDHMDB02457
Pubchem Compound ID935
Kegg IDC00291
ChemSpider ID909
WikipediaNickel
BioCyc IDNI%2b2
EcoCyc IDNI%2b2
Ligand ExpoNI

Enzymes

General function:
Involved in hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
Specific function:
Mediates magnesium influx to the cytosol
Gene Name:
mgtA
Locus Tag:
PA4825
Molecular weight:
100.1 kDa
Reactions
ATP + H(2)O + Mg(2+)(Out) = ADP + phosphate + Mg(2+)(In).

Transporters