Record Information
Version 1.0
Update Date 1/22/2018 12:54:54 PM
Metabolite IDPAMDB001663
Identification
Name: Nitrous oxide
Description:Nitrous oxide, commonly known as laughing gas, is a chemical compound with the formula N2O. It is an oxide of nitrogen. At room temperature, it is a colorless, non-flammable gas, with a slightly sweet odor and taste. N2O is produced naturally by microorganisms in soil through various types of nitrification and denitrification processes. (Wikipedia) Nitrous oxide production by Pseudomonas aeruginosa seems to result from the reduction of nitrite (NO2-) by nitrate (NO3-) reductase. (PMID 6347062)
Structure
Thumb
Synonyms:
  • Diazyne 1-oxide
  • Dinitrogen monoxide
  • Dinitrogen oxide
  • Distickstoffmonoxid
  • Factitious air
  • Gaz hilarant
  • Hyponitrous acid anhydride
  • Lachgas
  • Laughing gas
  • N2O
  • Nitral
  • Nitrogen monoxide
  • Nitrogen oxide
  • Nitrogen oxide (N2O)
  • Nitrogen protoxide
  • Nitrogenium oxydulatum
  • Nitrous oxide
  • NNO
  • Oxidodinitrogen(NN)
  • Oxyde nitreux
  • Protoxyde D'azote
  • Stickstoff(1)-oxid
Chemical Formula: N2O
Average Molecular Weight: 44.0128
Monoisotopic Molecular Weight: 44.001062632
InChI Key: GQPLMRYTRLFLPF-UHFFFAOYSA-N
InChI:InChI=1S/N2O/c1-2-3
CAS number: 10024-97-2
IUPAC Name:diazooxidane
Traditional IUPAC Name: nitrous oxide
SMILES:[O-][N+]#N
Chemical Taxonomy
Taxonomy DescriptionThis compound belongs to the class of inorganic compounds known as homogeneous other non-metal compounds. These are inorganic non-metallic compounds in which the largest atom belongs to the class of 'other nonmetals'.
Kingdom Inorganic compounds
Super ClassHomogeneous non-metal compounds
Class Homogeneous other non-metal compounds
Sub ClassNot Available
Direct Parent Homogeneous other non-metal compounds
Alternative Parents
Substituents
  • Homogeneous other non metal
  • Inorganic oxide
  • Acyclic compound
Molecular Framework Acyclic compounds
External Descriptors
Physical Properties
State: Liquid
Charge:0
Melting point: -90.81 °C
Experimental Properties:
PropertyValueSource
LogP:0.36PhysProp
Predicted Properties
PropertyValueSource
logP-0.021ChemAxon
pKa (Strongest Basic)-6.8ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area54.46 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity27.67 m3·mol-1ChemAxon
Polarizability2.54 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Biological Properties
Cellular Locations: Cytoplasm
Reactions:
Pathways: Not Available
Spectra
Spectra:
Spectrum TypeDescriptionSplash Key
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-0002-9000000000-2eee7435817186856ef7View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-001j-9000000000-d1a5381e3dd214cad7abView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-000t-9000000000-3ae2e01e3d626729760bView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-004l-9000000000-c53ff0d270e0310b3375View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-004i-9000000000-c8b9d8f80d3f41ad7f54View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-002f-9000000000-12c3fe456373daff732eView in MoNA
References
References:
  • Smith, M. S. (1983). "Nitrous oxide production by Escherichia coli is correlated with nitrate reductase activity." Appl Environ Microbiol 45:1545-1547. Pubmed: 6347062
Synthesis Reference: Not Available
Material Safety Data Sheet (MSDS) Not Available
External Links:
ResourceLink
CHEBI ID17045
HMDB IDHMDB35807
Pubchem Compound ID948
Kegg IDC00887
ChemSpider ID923
WikipediaNitrous_oxide
BioCyc IDNITROUS-OXIDE
EcoCyc IDNITROUS-OXIDE
Ligand ExpoN2O

Enzymes

General function:
Involved in iron ion binding
Specific function:
Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the reductase at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase
Gene Name:
norV
Locus Tag:
PA5351
Molecular weight:
6.3 kDa

Transporters