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Record Information |
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| Version |
1.0 |
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| Update Date |
1/22/2018 11:54:54 AM |
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Metabolite ID | PAMDB000940 |
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Identification |
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| Name: |
4-Hydroxy-L-threonine |
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| Description: | 4-hydroxy-L-threonine is a member of the chemical class known as Alpha Amino Acids and Derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon).4-hydroxyl-L-threonine is involved in pyridoxine biosynthesis. This result is consistent with a model in which 4-phospho-hydroxy-L-threonine (synonym, 3-hydroxyhomoserine phosphate), rather than 4-hydroxy-L-threonine, is an obligatory intermediate in pyridoxal 5'-phosphate biosynthesis. (PMID 8595869) |
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Structure |
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| Synonyms: | - (2S,3S)-2-amino-3,4-dihydroxybutanoate
- (2S,3S)-2-amino-3,4-dihydroxybutanoic acid
- 2-Amino-3,4-dihydroxy-(S-(R*,R*))-L-Threonate
- 2-Amino-3,4-dihydroxy-(S-(R*,R*))-L-Threonic acid
- 3-Hydroxyhomoserine
- a-amino-b,g-Dihydroxybutyrate
- a-amino-b,g-Dihydroxybutyric acid
- Alpha-Amino-beta,gamma-dihydroxybutyrate
- Alpha-Amino-beta,gamma-dihydroxybutyric acid
- Hydroxythreonine
- α-amino-β,γ-Dihydroxybutyrate
- α-amino-β,γ-Dihydroxybutyric acid
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Chemical Formula: |
C4H9NO4 |
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| Average Molecular Weight: |
135.1186 |
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| Monoisotopic Molecular
Weight: |
135.053157781 |
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| InChI Key: |
JBNUARFQOCGDRK-GBXIJSLDSA-N |
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| InChI: | InChI=1S/C4H9NO4/c5-3(4(8)9)2(7)1-6/h2-3,6-7H,1,5H2,(H,8,9)/t2-,3+/m1/s1 |
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| CAS
number: |
21768-45-6 |
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| IUPAC Name: | (2S,3S)-2-amino-3,4-dihydroxybutanoic acid |
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Traditional IUPAC Name: |
hydroxythreonine |
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| SMILES: | N[C@@H]([C@H](O)CO)C(O)=O |
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Chemical Taxonomy |
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Taxonomy Description | This compound belongs to the class of organic compounds known as hydroxy fatty acids. These are fatty acids in which the chain bears a hydroxyl group. |
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Kingdom |
Organic compounds |
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| Super Class | Lipids and lipid-like molecules |
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Class |
Fatty Acyls |
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| Sub Class | Fatty acids and conjugates |
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Direct Parent |
Hydroxy fatty acids |
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| Alternative Parents |
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| Substituents |
- Hydroxy fatty acid
- D-alpha-amino acid
- Alpha-amino acid or derivatives
- Alpha-amino acid
- Short-chain hydroxy acid
- Beta-hydroxy acid
- Amino fatty acid
- Hydroxy acid
- 1,3-aminoalcohol
- Secondary alcohol
- 1,2-diol
- Monocarboxylic acid or derivatives
- Carboxylic acid
- Carboxylic acid derivative
- Hydrocarbon derivative
- Primary amine
- Primary alcohol
- Organooxygen compound
- Organonitrogen compound
- Primary aliphatic amine
- Carbonyl group
- Amine
- Alcohol
- Aliphatic acyclic compound
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| Molecular Framework |
Aliphatic acyclic compounds |
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| External Descriptors |
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Physical Properties |
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| State: |
Not Available |
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| Charge: | 0 |
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Melting point: |
Not Available |
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| Experimental Properties: |
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| Predicted Properties |
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Biological Properties |
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| Cellular Locations: |
Cytoplasm |
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| Reactions: | |
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Pathways: |
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Spectra |
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| Spectra: |
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References |
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| References: |
- Kanehisa, M., Goto, S., Sato, Y., Furumichi, M., Tanabe, M. (2012). "KEGG for integration and interpretation of large-scale molecular data sets." Nucleic Acids Res 40:D109-D114. Pubmed: 22080510
- Keseler, I. M., Collado-Vides, J., Santos-Zavaleta, A., Peralta-Gil, M., Gama-Castro, S., Muniz-Rascado, L., Bonavides-Martinez, C., Paley, S., Krummenacker, M., Altman, T., Kaipa, P., Spaulding, A., Pacheco, J., Latendresse, M., Fulcher, C., Sarker, M., Shearer, A. G., Mackie, A., Paulsen, I., Gunsalus, R. P., Karp, P. D. (2011). "EcoCyc: a comprehensive database of Escherichia coli biology." Nucleic Acids Res 39:D583-D590. Pubmed: 21097882
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| Synthesis Reference: |
Not Available |
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| Material Safety Data Sheet (MSDS) |
Not Available |
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Links |
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| External Links: |
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